Histomorphometric Examination of Long-term Changes in Temporomandibular Joints After Mandibular Lengthening by Distraction Osteogenesis in Rabbits

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dc.contributor.authorMihmanlı, Ahmet
dc.contributor.authorDolanmaz, Doğan
dc.contributor.authorTüz, Hakan
dc.contributor.authorPampu, Alper
dc.contributor.authorDönmez, Hasan Hüseyin
dc.date.accessioned2020-03-26T18:30:41Z
dc.date.available2020-03-26T18:30:41Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective. The purpose of this study was to evaluate long-term histomorphometric changes in temporomandibular joints (TMJs) of rabbits after mandibular distraction osteogenesis (DO). Study Design. Twenty-six rabbits were used in this study. Two of them served as control subjects, and the remaining 24 underwent DO procedures in their left mandibular bodies. After a latency period of 5 days, 5 mm lengthening was performed at a rate of 1 mm/d. The rabbits in the experimental group were randomly divided into 4 subgroups and killed after 1, 2, 4, and 6 months. TMJs from both sides were harvested and prepared with hematoxylin and eosin stain for histomorphometric examination under an optical microscope. Results. Compared with control subjects and nondistracted sides, fibrous articular, proliferative, and hypertrophic areas were significantly increased (P < .05) in the first 2 months in distracted sides. The changes were insignificant in the fourth and sixth postoperative months. Conclusion. Unilateral mandibular distraction of 5 mm was found to be well tolerated and no degenerative changes were observed histologically in the rabbit TMJs in the long-term period.en_US
dc.identifier.citationMihmanlı, A., Dolanmaz, D., Tüz, H., Pampu, Al., Dönmez, H. H., (2012). Histomorphometric Examination of Long-term Changes in Temporomandibular Joints After Mandibular Lengthening by Distraction Osteogenesis in Rabbits. Oral Surgery Oral Medicine Oral Pathology Oral Radiology, 113(5), 600-603. Doi:10.1016/j.tripleo.2011.04.043
dc.identifier.doi10.1016/j.tripleo.2011.04.043en_US
dc.identifier.endpage603en_US
dc.identifier.issn2212-4403en_US
dc.identifier.issn1528-395Xen_US
dc.identifier.issue5en_US
dc.identifier.pmid22676985en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage600en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.tripleo.2011.04.043
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28112
dc.identifier.volume113en_US
dc.identifier.wosWOS:000303402200015en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorDolanmaz, Doğan
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofOral Surgery Oral Medicine Oral Pathology Oral Radiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleHistomorphometric Examination of Long-term Changes in Temporomandibular Joints After Mandibular Lengthening by Distraction Osteogenesis in Rabbitsen_US
dc.typeArticleen_US

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