Assessment of the effects of antihistamine drugs on mood, sleep quality, sleepiness, and dream anxiety

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dc.contributor.authorOzdemir, Pinar Guzel
dc.contributor.authorKaradag, Ayse Serap
dc.contributor.authorSelvi, Yavuz
dc.contributor.authorBoysan, Murat
dc.contributor.authorBilgili, Serap Gunes
dc.contributor.authorAydin, Adem
dc.contributor.authorOnder, Sevda
dc.date.accessioned2020-03-26T18:49:30Z
dc.date.available2020-03-26T18:49:30Z
dc.date.issued2014
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective. There are limited comparative studies on classic and new-generation antihistamines that affect sleep quality and mood. The purpose of this study was to determine and compare the effects of classic and new-generation antihistamines on sleep quality, daytime sleepiness, dream anxiety, and mood. Methods. Ninety-two patients with chronic pruritus completed study in the dermatology outpatient clinic. Treatments with regular recommended therapeutic doses were administered. The effects of antihistaminic drugs on mood, daytime sleepiness, dream anxiety, and sleep quality were assessed on the first day and 1 month aft er. Results. Outpatients who received cetirizine and hydroxyzine treatments reported higher scores on the depression, anxiety, and fatigue sub-scales than those who received desloratadine, levocetirizine, and rupatadine. Pheniramine and rupatadine were found to be associated with daytime sleepiness and better sleep quality. UKU side effects scale scores were significantly elevated among outpatients receiving pheniramine. Classic antihistamines increased daytime sleepiness and decreased the sleep quality scores. New-generation antihistamines reduced sleep latency and dream anxiety, and increased daytime sleepiness and sleep quality. Conclusion. Both antihistamines, significantly increased daytime sleepiness and nocturnal sleep quality. Daytime sleepiness was significantly predicted by rupadatine and pheniramine treatment. Cetirizine and hydroxyzine, seem to have negative influences on mood states. Given the extensive use of antihistamines in clinical settings, these results should be more elaborately examined in further studies.en_US
dc.identifier.doi10.3109/13651501.2014.907919en_US
dc.identifier.endpage168en_US
dc.identifier.issn1365-1501en_US
dc.identifier.issn1471-1788en_US
dc.identifier.issue3en_US
dc.identifier.pmid24673474en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage161en_US
dc.identifier.urihttps://dx.doi.org/10.3109/13651501.2014.907919
dc.identifier.urihttps://hdl.handle.net/20.500.12395/30625
dc.identifier.volume18en_US
dc.identifier.wosWOS:000344473100003en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS LTDen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAntihistaminesen_US
dc.subjectsleep qualityen_US
dc.subjectmooden_US
dc.subjectdream anxietyen_US
dc.subjectdaytime sleepinessen_US
dc.titleAssessment of the effects of antihistamine drugs on mood, sleep quality, sleepiness, and dream anxietyen_US
dc.typeArticleen_US

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