Prognostic value of serum zinc levels in critically ill patients

Basit Öğe Kaydı
dc.contributor.authorCander, Basar
dc.contributor.authorDundar, Zerrin Defne
dc.contributor.authorGul, Mehmet
dc.contributor.authorGirisgin, Sadik
dc.date.accessioned2020-03-26T18:15:48Z
dc.date.available2020-03-26T18:15:48Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPurpose: We investigated the hypothesis that a decline in serum zinc concentrations among critically ill patients is related to mortality, length of stay in the intensive care unit, and Acute Physiology and Chronic Health Evaluation II and Sequential Organ Failure Assessment (SOFA) scores. Materials and Methods: All the patients (>= 18 years old) presenting to the intensive care unit from September 2009 through November 2009 were enrolled the study. Patients' demographic characteristics and Acute Physiology and Chronic Health Evaluation and SOFA scores were recorded. Blood samples were collected within 24 hours after admission and analyzed for serum zinc, copper, C-reactive protein, and albumin levels. Patients were followed up for mortality and length of stay in the intensive care unit for 28 days. Results: A total of 36 patients, with a median age of 70.5 years (range, 18-87 years), were enrolled during the study period. Serum zinc levels were found to be inversely correlated with SOFA scores (r = -0.41, P < .01). Patients with SOFA scores of 8 or higher had significantly lower serum zinc levels compared with patients with SOFA scores lower than 8 (6.74 +/- 1.63 and 9.17 +/- 2.76 mu mol/L, respectively; P < .01). Conclusion: The result of this study supports the fact that organ failure and critical illness lead to a decline in serum zinc concentrations and that administration of zinc may be beneficial for critically ill patients. (C) 2011 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.jcrc.2010.06.002en_US
dc.identifier.endpage46en_US
dc.identifier.issn0883-9441en_US
dc.identifier.issn1557-8615en_US
dc.identifier.issue1en_US
dc.identifier.pmid20655701en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage42en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.jcrc.2010.06.002
dc.identifier.urihttps://hdl.handle.net/20.500.12395/26755
dc.identifier.volume26en_US
dc.identifier.wosWOS:000287465900008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B SAUNDERS CO-ELSEVIER INCen_US
dc.relation.ispartofJOURNAL OF CRITICAL CAREen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectZincen_US
dc.subjectOrgan failureen_US
dc.subjectCritically illen_US
dc.subjectCritical careen_US
dc.subjectMortalityen_US
dc.titlePrognostic value of serum zinc levels in critically ill patientsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu