Antimicrobial activities, toxicity and phenolic composition of Asphodeline anatolica E. Tuzlaci leaf extracts from Turkey

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dc.contributor.authorMarino, Andreana
dc.contributor.authorZengin, Gökhan
dc.contributor.authorNostro, Antonia
dc.contributor.authorGinestra, Giovanna
dc.contributor.authorDugo, Paola
dc.contributor.authorCacciola, Francesco
dc.contributor.authorMiceli, Natalizia
dc.date.accessioned2020-03-26T19:23:05Z
dc.date.available2020-03-26T19:23:05Z
dc.date.issued2016
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe antimicrobial activity of acetone, methanol and aqueous extracts of Asphodeline anatolica E. Tuzlaci leaves was evaluated against American type culture collection, food and clinical isolates (Listeria monocytogenes and Staphylococcus aureus including methicillin-resistant strains-MRSA). Biofilm formation, toxicity and characterisation of the polyphenolic content were analysed. The acetone extract demonstrated a higher antibacterial activity against S. aureus including MRSA strains, L. monocytogenes and Pseudomonas aeruginosa than against other extracts. No effect was observed in biofilm formation. The extracts resulted non-toxic against Artemia salina Leach. The phytochemical screening of extracts indicated that they mainly contained six polyphenols identified as catechin 3-O-gallate, protocatechuic acid, diosmin, rutin, cirsimaritin and kaempferol glucoside. This study is the first report on antimicrobial activity and phenolic content of A. anatolica and contributes to enrich the literature data on the biological properties of this plant. A. anatolica leaves have a potential as source of natural antimicrobial compounds.en_US
dc.identifier.doi10.1080/14786419.2015.1129330en_US
dc.identifier.endpage2623en_US
dc.identifier.issn1478-6419en_US
dc.identifier.issn1478-6427en_US
dc.identifier.issue22en_US
dc.identifier.pmid26727992en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2620en_US
dc.identifier.urihttps://dx.doi.org/10.1080/14786419.2015.1129330
dc.identifier.urihttps://hdl.handle.net/20.500.12395/33264
dc.identifier.volume30en_US
dc.identifier.wosWOS:000387296300018en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS LTDen_US
dc.relation.ispartofNATURAL PRODUCT RESEARCHen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAntimicrobialsen_US
dc.subjectbiofilmen_US
dc.subjectMRSAen_US
dc.subjectListeria monocytogenesen_US
dc.subjectHPLC analysisen_US
dc.subjectArtemia salina testen_US
dc.titleAntimicrobial activities, toxicity and phenolic composition of Asphodeline anatolica E. Tuzlaci leaf extracts from Turkeyen_US
dc.typeArticleen_US

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