Serum magnesium concentrations in type 1 diabetic patients: Relation to early atherosclerosis

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dc.contributor.authorAtabek, ME
dc.contributor.authorKurtoglu, S
dc.contributor.authorPirgon, O
dc.contributor.authorBaykara, M
dc.date.accessioned2020-03-26T17:04:17Z
dc.date.available2020-03-26T17:04:17Z
dc.date.issued2006
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractHypomagnesemia and sub-clinical atherosclerosis are common in type 1 diabetic patients, and are especially common in poorly controlled and chronically treated diabetics. The aim of this study was to evaluate the relationships between serum magnesium (Mg) and intima-media thickness (IMT), and functions, of common carotid artery (CCA), accepted as markers of early carotid atherosclerosis in type I diabetic patients. Serum magnesium levels were measured in 51 diabetic patients (26 girls and 25 boys). Age, duration of diabetes as well as major cardiovascular risk factors, including anthropometric and metabolic parameters were matched between girls and boys. CCA structure and functions were measured by ultrasonography as IMT, cross-sectional compliance (CSC), cross-sectional distensibility (CSD), diastolic wall stress (DWS), and incremental elastic modulus (IEM). The difference for serum Mg was significant between diabetic girls and boys (0.75 +/- 0.09 mmol/l versus 0.86 +/- 0.14 mmol/l; p = 0.02). Mg levels were correlated with IMT (r = -0.58, p = 0.004) and DWS (r = -0.49, p = 0.01) in girls and with IMT (r = -0.55, p = 0.007) and DWS (r = -0.46, p = 0.03) in boys. In a multivariate regression model, Mg, systolic blood pressure and waist-hip ratio emerged as independent correlates for mean IMT in girls with the total variance explained being 63%, and Mg and triglycerides emerged as independent correlates for mean IMT in boys with the total variance explained being 68%. Mg did not emerge as independent correlates for mean DWS in both girls and boys. Serum magnesium levels in children and adolescent patients with type I diabetes are associated with early atherosclerosis. (c) 2005 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.diabres.2005.09.002en_US
dc.identifier.endpage47en_US
dc.identifier.issn0168-8227en_US
dc.identifier.issn1872-8227en_US
dc.identifier.issue1en_US
dc.identifier.pmid16214256en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage42en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.diabres.2005.09.002
dc.identifier.urihttps://hdl.handle.net/20.500.12395/20670
dc.identifier.volume72en_US
dc.identifier.wosWOS:000237094100007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherELSEVIER IRELAND LTDen_US
dc.relation.ispartofDIABETES RESEARCH AND CLINICAL PRACTICEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjecttype 1 diabetesen_US
dc.subjectatherosclerosisen_US
dc.subjectmagnesiumen_US
dc.titleSerum magnesium concentrations in type 1 diabetic patients: Relation to early atherosclerosisen_US
dc.typeArticleen_US

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