Criteria sets for primary Sjogren's syndrome are not adequate for those presenting with extraglandular organ involvements as their dominant clinical features

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dc.contributor.authorKabasakal, Yasemin
dc.contributor.authorKitapcioglu, Gul
dc.contributor.authorKarabulut, Gonca
dc.contributor.authorTezcan, Mehmet
dc.contributor.authorBalkarli, Ayse
dc.contributor.authorAksoy, Adem
dc.contributor.authorYavuz, Aule
dc.date.accessioned2020-03-26T19:34:40Z
dc.date.available2020-03-26T19:34:40Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPatients with primary Sjogren's syndrome (pSS) may go undiagnosed or be misclassified due to the insidious nature and wide spectrum of the disease. The available several classification criteria emphasize glandular findings. We aimed to analyze the efficiency of various classification criteria sets in patients diagnosed on the clinical basis by expert opinion and to compare those pSS patients who fulfilled these criteria with those who did not. This is a multicenter study in which 834 patients from 22 university-based rheumatology clinics are included. Diagnosis of pSS was made on the clinical basis by the expert opinion. In this study, we only interviewed patients once and collected available data from the medical records. The European criteria, American-European Consensus Group (AECG) and American College of Rheumatology (ACR) Sjogren's criteria were applied. Majority of the patients were women (F/M was 20/1). The median duration from the first pSS-related symptom to diagnosis was significantly shorter in men (2.5 +/- 2.3 vs 4.3 +/- 5.9 years) (p = 0 < 0.016). When the European, AECG and ACR Sjogren's criteria were applied, 666 patients (79.9%) satisfied at least one of them. In total, 539 patients (64.4%) satisfied the European, 439 (52.6%) satisfied the AECG, and 359 (43%) satisfied the ACR criteria. Among the entire group, 250 patients (29.9%) satisfied all and 168 (20.1%) met none of the criteria. The rates of extraglandular organ involvements were not different between patients who met at least one of the criteria sets and those who met none. There is an urgent need for the modification of the pSS criteria sets to prevent exclusion of patients with extraglandular involvements as the dominant clinical features.en_US
dc.description.sponsorshipRheumatology Society of Turkey (TRD)en_US
dc.description.sponsorshipThis study was funded by the Rheumatology Society of Turkey (TRD) (award recipient is Yasemin Kabasakal, M.D.).en_US
dc.identifier.doi10.1007/s00296-017-3691-8en_US
dc.identifier.endpage684en_US
dc.identifier.issn0172-8172en_US
dc.identifier.issn1437-160Xen_US
dc.identifier.issue5en_US
dc.identifier.pmid28289872en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage675en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s00296-017-3691-8
dc.identifier.urihttps://hdl.handle.net/20.500.12395/34936
dc.identifier.volume37en_US
dc.identifier.wosWOS:000399829800001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSPRINGER HEIDELBERGen_US
dc.relation.ispartofRHEUMATOLOGY INTERNATIONALen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectSjogren's syndromeen_US
dc.subjectClassification criteriaen_US
dc.subjectExtraglandular involvementen_US
dc.subjectEpidemiologyen_US
dc.titleCriteria sets for primary Sjogren's syndrome are not adequate for those presenting with extraglandular organ involvements as their dominant clinical featuresen_US
dc.typeArticleen_US

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