Effect of 1,25 (OH)2 D3 Treatment on Lipid Levels in Uremic Hemodialysis Patients

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dc.contributor.authorYeksan, M.
dc.contributor.authorTürk, S.
dc.contributor.authorPolat, M.
dc.contributor.authorÇığlı, A.
dc.contributor.authorErdoğan, Y.
dc.date.accessioned2020-03-26T16:24:18Z
dc.date.available2020-03-26T16:24:18Z
dc.date.issued1992
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe aim of this study was to evaluate the effect of 1,25 (OH)2D3 treatment on lipid levels in uremic hemodialysis (HD) patients. Thirty-one HD patients who had never been treated with vitamin D nor related drugs and 12 healthy subjects with normal renal functions were studied. Uremic HD patients were randomly divided into two groups. Sixteen uremic HD patients were treated with oral calcitriol (0.5 ?g/day) for 8 weeks. 13 uremic HD patients and 12 healthy subjects were given placebo. In all these cases before and after 8 weeks of treatments; serum total lipid, total cholesterol, HDL-cholesterol, LDL-cholesterol and triglycerid levels were determined. After calcitriol treatment, triglycerid levels were significantly decreased. But total lipid, cholesterol, HDL-cholesterol and LDL-cholesterol levels did not significantly change. In the other two groups there were no significant changes. These results show that calcitriol treatment has a positive effect on triglycerid levels in uremic HD patients. This effect of mechanism of calcitriol treatment has not been known yet. But it could be due to regulation carbohydrates metabolism and normalization of parathormone (PTH) levels.en_US
dc.identifier.citationYeksan, M., Türk, S., Polat, M., Çığlı, A., Erdoğan, Y., (1992). Effect of 1,25 (OH)2 D3 Treatment on Lipid Levels in Uremic Hemodialysis Patients. International Journal of Artificial Organs, 15(12), 704-707.
dc.identifier.endpage707en_US
dc.identifier.issn0391-3988en_US
dc.identifier.issue12en_US
dc.identifier.pmid1493945en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage704en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/16154
dc.identifier.volume15en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÇığlı, A.
dc.language.isoenen_US
dc.relation.ispartofInternational Journal of Artificial Organsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCalcitriol
dc.subjectHemodialysis
dc.subjectLipids
dc.titleEffect of 1,25 (OH)2 D3 Treatment on Lipid Levels in Uremic Hemodialysis Patientsen_US
dc.typeArticleen_US

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