L-thyroxine-induced hyperthyroidism affects elements and zinc in rats

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dc.contributor.authorBaltaci, A. K.
dc.contributor.authorMogulkoc, R.
dc.contributor.authorBelviranli, M.
dc.date.accessioned2020-03-26T18:42:24Z
dc.date.available2020-03-26T18:42:24Z
dc.date.issued2013
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThere is a significant relation between thyroid hormones and zinc. The establishment of low blood zinc levels in hypothyroidism as opposed to high blood zinc levels in hyperthyroidism testifies to this relation. The present study aims to examine the changes in levels of some elements in sera of rats with induced hyperthyroidism as well as the relation between these changes and zinc. Thirty adult male rats of Sprague-Dawley type were equally allocated to three groups, particularly Group 1: General Control, Group 2: Sham-hyperthyroidism Group, and Group 3: Hyperthyroidism Group. Subsequent to decapitating the animals, their blood samples were taken and analyzed with the help of atomic emission spectrophotometer in terms of serum levels of zinc, selenium, calcium, magnesium, phosphorus, chromium, copper and iron. The levels of zinc, selenium and calcium were higher (p<0.01), while those of chromium, copper, iron and phosphorus were lower (p<0.01) in Group 3, relative to groups 1 and 2. These parameters were not different in groups 1 and 2. The results obtained from the study indicate that hyperthyroidism brings about some changes in the levels of some elements in rats. These changes might be associated with the elevation of zinc levels in hyperthyroidism (Tab. 2, Ref. 41). Full Text in PDF www.elis.sk.en_US
dc.description.sponsorshipSUBAPK (Scientific Research Project Coordinator of Selcuk University)Selcuk University [TF 2002-086]en_US
dc.description.sponsorshipThis study was supported in part by SUBAPK (Scientific Research Project Coordinator of Selcuk University). Project number is TF 2002-086.en_US
dc.identifier.doi10.4149/BLL_2013_027en_US
dc.identifier.endpage128en_US
dc.identifier.issn0006-9248en_US
dc.identifier.issn1336-0345en_US
dc.identifier.issue3en_US
dc.identifier.pmid23406177en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage125en_US
dc.identifier.urihttps://dx.doi.org/10.4149/BLL_2013_027
dc.identifier.urihttps://hdl.handle.net/20.500.12395/29622
dc.identifier.volume114en_US
dc.identifier.wosWOS:000315758300004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCOMENIUS UNIVen_US
dc.relation.ispartofBRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjecthyperthyroidismen_US
dc.subjectzincen_US
dc.subjectseleniumen_US
dc.subjecttrace elementsen_US
dc.subjectraten_US
dc.titleL-thyroxine-induced hyperthyroidism affects elements and zinc in ratsen_US
dc.typeArticleen_US

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