Synthesis and antimicrobial assessment of Fe3+ inclusion complex of p-tert-Butylcalix[4]arene diamide derivative

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dc.authorid0000-0002-6088-8369
dc.contributor.authorChandio, Anwar Ali.
dc.contributor.authorMemon, Ayaz Ali.
dc.contributor.authorMemon, Shahabuddin.
dc.contributor.authorMemon, Fakhar N.
dc.contributor.authorPanhwar, Qadeer Khan.
dc.contributor.authorDurmaz, Fatih.
dc.contributor.authorNizamani, Shafi Muhammad.
dc.contributor.authorBrohi, Nazir Ahmed.
dc.date.accessioned2020-03-26T20:19:19Z
dc.date.available2020-03-26T20:19:19Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Fen Fakültesi, Kimya Bölümüen_US
dc.description.abstractPresent study deals with the synthesis of the p-tert-butylcalix[4]arene diamide derivative as ligand (L) and its Fe3+ complex, followed by its characterization using TLC and FT-IR, while UV-Vis and Job's plot study were performed for complex formation. Antimicrobial activity of the derivative (L) and its metal complex was carried out by the disc diffusion method against bacteria (Escherichia coli and Staphylococcus albus) and fungi (R. stolonifer). Different concentrations of the derivative (L) (6, 3, 1.5, 0.75, and 0.37 mu g/mL) and its Fe3+ complex were prepared, and Mueller-Hinton agar was used as the medium for the growth of microorganisms. Six successive dilutions of the derivative (L) and Fe3+ complex were used against microorganisms. Two successive dilutions (6 and 3 mu g/mL) of the derivative (L) showed antibacterial action against both Gram-positive and Gram-negative bacteria. In addition, three successive dilutions (6, 3, and 1.5 mu g/mL) of the derivative (L) showed antifungal activity. However, all of six dilutions of the Fe3+ complex showed antimicrobial activity. Derivative (L) showed 3 and 1.5g/mL minimum inhibitory concentrations (MIC) against bacteria and fungi, respectively. On the contrary, its Fe3+ complex showed 0.37g/mL value of MIC against bacteria and fungi. Hence, Fe3+ complex of the derivative (L) was found to be a more effective antimicrobial agent against selected bacteria and fungi than the diamide derivative (L).en_US
dc.identifier.citationChandio, A. A., Ali Memon, A., Memon, S., Memon, F. N., Panhwar, Q. K., Durmaz, F., Nizamani, S. M., Brohi, N. A. (2019). Synthesis and Antimicrobial Assessment of Fe3+ Inclusion Complex of p-tert-Butylcalix [4] arene Diamide Derivative. Journal of Chemistry, 2019, 1-8.
dc.identifier.doi10.1155/2019/2534072en_US
dc.identifier.issn2090-9063en_US
dc.identifier.issn2090-9071en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://dx.doi.org/10.1155/2019/2534072
dc.identifier.urihttps://hdl.handle.net/20.500.12395/38216
dc.identifier.volume2019
dc.identifier.wosWOS:000464784800001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorDurmaz, Fatih.
dc.language.isoenen_US
dc.publisherHINDAWI LTDen_US
dc.relation.ispartofJOURNAL OF CHEMISTRYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectFe3+
dc.subjectp-tert-Butylcalix[4]arene
dc.subjectdiamide derivative
dc.subjectSynthesis and antimicrobial assessment
dc.titleSynthesis and antimicrobial assessment of Fe3+ inclusion complex of p-tert-Butylcalix[4]arene diamide derivativeen_US
dc.typeArticleen_US

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