Calculation of intracranial volume in Akkaraman and Kangal Akkaraman sheep by stereology and computed tomography
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Dosyalar
Tarih
2024
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Selçuk Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Koyun ırklarının intrakraniyal hacminin bilinmesi ırk ayrımı ve klinik bilimler açısından önemlidir. Bu çalışmanın amacı Türkiye’deki koyun varlığının büyük bir çoğunluğunu oluşturan Akkaraman ve Kangal Akkaraman koyun ırklarının intrakraniyal hacimlerinin ve ölçüm yöntemlerinin karşılaştırılmasıdır.
Gereç ve Yöntem: Çalışmada sağlıklı erkek 6-8 aylık yaşta 10 adet Akkaraman ve 10 adet Kangal Akkaraman koyununa ait başlar kullanıldı. Koyun başları rostral-caudal yönde, kesit oryantasyonuna referans sağlamak için sert damağa dik, 0,6 mm dedektör kalınlığı ile aksiyel (transversal) planda görüntüleme yapıldı. Aksiyel görüntülerin rekonstrüksiyonu 0,65 mm kesit kalınlığı ile yapıldı. Koyun başlarının intrakraniyal hacimleri bilgisayarlı tomografi (BT) görüntüleri kullanılarak Cavalieri prensibi ile ölçüldü. Ek olarak Slicer 5.3 programı ile intrakraniyal alanın üç boyutlu modelleri oluşturuldu ve program araçları ile hacmi hesaplandı. Hacim ölçümü sonucu elde edilen veriler bağımsız gruplarda t testi, metotlar arasındaki karşılaştırma ise Bland-Altman testi ile SPSS 26.0 paket programında analiz edildi.
Bulgular: Akkaraman koyununun intrakraniyal hacminin ortalama değerlerinin Akkaraman koyunlarından istatistiksel olarak anlamlı ve büyük olduğu bulundu (P<0.01). Stereolojik yöntem ve BT modelleri ile hesaplanan intrakraniyal hacimlerin istatistiksel olarak karşılaştırılması sonucunda iki metot arasında fark olmadığı tespit edildi. (P>0.05).
Öneri: İntrakraniyal hacmin doğru bir şekilde hesaplanması, beyin ve sinir sistemi hastalıklarının teşhis ve tedavisinde büyük bir öneme sahiptir. Bu çalışmanın sonuçları, Akkaraman ve Kangal Akkaraman koyunlarında intrakraniyal hacmin belirlenmesinin hastalıkların tanısında klinik bilimlere önemli katkılar sağlayabileceğini göstermektedir. Aynı zamanda veteriner hekimler ve araştırmacılar için hastalıkların daha iyi anlaşılması ve etkili tedavi yöntemlerinin geliştirilmesinde önemli bir rehberlik sağlayabilir. Bu nedenle, çalışmanın sonuçları veteriner tıp ve ilgili disiplinlerde yapılan araştırmaları yönlendirebilir ve klinik uygulamalar için önemli bir temel oluşturabilir.
Aim: Knowing the intracranial volume of sheep breeds is important for breed segregation and clinical sciences. The aim of this study is to compare the intracranial volumes and measurement methods of Akkaraman and Kangal Akkaraman sheep breeds, which constitute the majority of sheep in Turkey. Materials and Methods: In the study, the heads of 10 healthy male Akkaraman and 10 Kangal Akkaraman sheep aged 6-8 months were used. The sheep heads were imaged in the rostral-caudal direction, perpendicular to the hard palate to provide reference for the section orientation, in the axial (transversal) plane with a detector thickness of 0.6 mm. Reconstruction of the axial images was done with a slice thickness of 0.65 mm. Intracranial volumes of the sheep heads were measured using computerized tomography (CT) images with the Cavalieri principle. In addition, three-dimensional models of the intracranial area were created with the Slicer 5.3 program and the volume was calculated with the program tools. The data obtained from volume measurement were analyzed with the t-test in independent groups, and comparison between methods was analyzed with the Bland-Altman analysis in the SPSS 26.0 package program. Results: The mean values of intracranial volume of Akkaraman sheep were found to be statistically significant and greater than Akkaraman sheep (P<0.01). As a result of statistical comparison of intracranial volumes calculated with stereological method and CT models, no difference was found between the two methods (P>0.05). Conclusion: Accurate calculation of intracranial volume is of great importance in the diagnosis and treatment of brain and nervous system diseases. The results of this study show that the determination of intracranial volume in Akkaraman and Kangal Akkaraman sheep can provide significant contributions to clinical sciences in the diagnosis of diseases. Therefore, it can also provide important guidance for veterinarians and researchers in better understanding diseases and developing effective treatment methods. Therefore, the results of the study can guide research in veterinary medicine and related disciplines and provide an important basis for clinical applications.
Aim: Knowing the intracranial volume of sheep breeds is important for breed segregation and clinical sciences. The aim of this study is to compare the intracranial volumes and measurement methods of Akkaraman and Kangal Akkaraman sheep breeds, which constitute the majority of sheep in Turkey. Materials and Methods: In the study, the heads of 10 healthy male Akkaraman and 10 Kangal Akkaraman sheep aged 6-8 months were used. The sheep heads were imaged in the rostral-caudal direction, perpendicular to the hard palate to provide reference for the section orientation, in the axial (transversal) plane with a detector thickness of 0.6 mm. Reconstruction of the axial images was done with a slice thickness of 0.65 mm. Intracranial volumes of the sheep heads were measured using computerized tomography (CT) images with the Cavalieri principle. In addition, three-dimensional models of the intracranial area were created with the Slicer 5.3 program and the volume was calculated with the program tools. The data obtained from volume measurement were analyzed with the t-test in independent groups, and comparison between methods was analyzed with the Bland-Altman analysis in the SPSS 26.0 package program. Results: The mean values of intracranial volume of Akkaraman sheep were found to be statistically significant and greater than Akkaraman sheep (P<0.01). As a result of statistical comparison of intracranial volumes calculated with stereological method and CT models, no difference was found between the two methods (P>0.05). Conclusion: Accurate calculation of intracranial volume is of great importance in the diagnosis and treatment of brain and nervous system diseases. The results of this study show that the determination of intracranial volume in Akkaraman and Kangal Akkaraman sheep can provide significant contributions to clinical sciences in the diagnosis of diseases. Therefore, it can also provide important guidance for veterinarians and researchers in better understanding diseases and developing effective treatment methods. Therefore, the results of the study can guide research in veterinary medicine and related disciplines and provide an important basis for clinical applications.
Açıklama
Anahtar Kelimeler
3B Modelleme, Akkaraman Koyunu, İntrakraniyal Hacim, Kangal Akkaraman Koyunu, Stereoloji, 3D Modeling, Akkaraman Sheep, Kangal Akkaraman Sheep, Intracranial Volume, Stereology
Kaynak
Eurasian Journal of Veterinary Sciences
WoS Q Değeri
Scopus Q Değeri
Cilt
40
Sayı
3
Künye
Baş-Ekici H. and Beşoluk K. (2024). Calculation of Intracranial Volume in Akkaraman and Kangal Akkaraman Sheep by Stereology and Computed Tomography, Eurasian J Vet Sci, 40, 3, 101-106. 10.15312/EurasianJVetSci.2024.433
