In vitro dentine permeability evaluation of HEMA-based (desensitizing) products using split-chamber model following in vivo application in the dog

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dc.contributor.authorDuran, I
dc.contributor.authorSengun, A
dc.contributor.authorYildirim, T
dc.contributor.authorOzturk, B
dc.date.accessioned2020-03-26T16:57:21Z
dc.date.available2020-03-26T16:57:21Z
dc.date.issued2005
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe aim of this study was to evaluate in vitro dentine permeability evaluation of 2-Hydroxyethyl methacrylate (HEMA)-based desensitizing products using split-chamber model following in vivo application in the dogs for three experimental time periods of 1 week, 1 month and 3 months. Buccal enamel of upper and lower canines of nine young dogs was removed and flat dentinal surface was obtained using a water-cooled diamond bur. The dentinal surface divided into four quarters, three experimental and a control. Health-Dent and Gluma Desensitizing agent and Single bond were applied to respective quarters of one tooth, according to manufacturers' instructions. The last quarters were left as control without any applications. For the each experimental period, 10 dentine samples from each group including control were used to measure the hydraulic conductance values. The dentine discs were placed pulp-side down in a split-chamber device in which the plastic spacers containing the rubber 0 rings have a surface area of 1 mm(2) and permeability was measured by fluid filtration. The data were expressed as hydraulic conductance (Lp). Differences in dentine permeability obtained for the desensitizing agents against the control were tested for statistical significance using Kruskal-Wallis one-way anova and Bonferroni-adjusted Mann-Whitney U-tests. Differences in permeability in three time periods for each desensitizing agent were analysed using Friedman's anova and Wilcoxon signed rank tests. All desensitizing applications caused decreased Lp values compared with the control Lp value at the end of 1 week. In the 1-month samples, between the Lp values of Single bond and control, no statistical difference was found (P > 0.05). At the end of the 3-month period, the Gluma Desensitizing agent had the lowest the Lp value (P < 0.05). The result of this study is that the topical application of desensitizing agents led to decrease in dentine permeability in the dog model. The Gluma Desensitizing agent provide the more lasting tubule-occluding effect than the other material tested in this model.en_US
dc.identifier.doi10.1111/j.1365-2842.2004.01132.xen_US
dc.identifier.endpage38en_US
dc.identifier.issn0305-182Xen_US
dc.identifier.issn1365-2842en_US
dc.identifier.issue1en_US
dc.identifier.pmid15634299en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage34en_US
dc.identifier.urihttps://dx.doi.org/10.1111/j.1365-2842.2004.01132.x
dc.identifier.urihttps://hdl.handle.net/20.500.12395/19767
dc.identifier.volume32en_US
dc.identifier.wosWOS:000225949900006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofJOURNAL OF ORAL REHABILITATIONen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjecthypersensitivityen_US
dc.subjectsplit chamberen_US
dc.subjectdentine permeabilityen_US
dc.subjectdesensitizing agentsen_US
dc.subjectin vivo dog studyen_US
dc.titleIn vitro dentine permeability evaluation of HEMA-based (desensitizing) products using split-chamber model following in vivo application in the dogen_US
dc.typeArticleen_US

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