Fine needle aspiration biopsy of thyroid nodules: cytologic and histopathologic correlation of 1096 patients

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dc.contributor.authorUgurluoglu, Ceyhan
dc.contributor.authorDobur, Fatma
dc.contributor.authorKarabagli, Pinar
dc.contributor.authorCelik, Zeliha Esin
dc.date.accessioned2020-03-26T19:06:00Z
dc.date.available2020-03-26T19:06:00Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractVia routinely used thyroid function tests, scintigraphy and ultrasonography (USG), important information is obtained in the clinical and diagnostic practice for thyroid nodules. However, the distinction between benign and malignant lesions cannot precisely be performed with these tests. Thyroid fine needle aspiration biopsy (FNAB) is considered the most reliable diagnostic method in the differentiation between benign and malignant thyroid nodules. It has recently been likely to perform aspiration from deeper nodules via the implemention of FNAB along with USG. Today, in cytopathological examination of thyroid FNAB, standardized Bethesda System for Reporting Thyroid Cytopathology (BSRTC) system is used. Here, FNAB was performed in 1096 patients with thyroid nodules in the Medical School of Selcuk University between January 2009 and July 2014. Patients consisted of 919 women and 177 men between 12 and 87 years of age. Evaluated via BSRTC, the results were classified as unsatisfactory, benign, atypia (or follicular lesions) of undetermined significance (AUS), follicular neoplasm or lesions suspicious for follicular neoplasm (FN), suspected malignant and malignant. After FNAB, 183 patients were operated and evaluated histopathologically. Histological malignancy rates of the categories were as follows: 16% (5), 15% (6) 14% (1) 60% (9), 72% (18) and 97% (63), respectively. In our study, we aimed to compare FNAB results of thyroid nodules with histopathology results after thyroidectomy and to show the sensitivity and specificity of FNAB technique to be higher in the follow-up and diagnosis of thyroid lesions. Given the malignancy detection rate in the follow-up of patients whose cytology was reported as inadequate, we also consider follow-ups are important in these patients.en_US
dc.identifier.endpage14805en_US
dc.identifier.issn1936-2625en_US
dc.identifier.issue11en_US
dc.identifier.pmid26823807en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage14800en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/32169
dc.identifier.volume8en_US
dc.identifier.wosWOS:000368140100115en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherE-CENTURY PUBLISHING CORPen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectThyroiden_US
dc.subjectfine needle aspiration biopsyen_US
dc.subjectbethesdaen_US
dc.titleFine needle aspiration biopsy of thyroid nodules: cytologic and histopathologic correlation of 1096 patientsen_US
dc.typeArticleen_US

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