Antimicrobial and mechanical properties of dental resin composite containing bioactive glass

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dc.contributor.authorKorkut, Emre
dc.contributor.authorTorlak, Emrah
dc.contributor.authorAltunsoy, Mustafa
dc.date.accessioned2020-03-26T19:23:06Z
dc.date.available2020-03-26T19:23:06Z
dc.date.issued2016
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground: The aim of this study was to evaluate the antimicrobial efficacy and mechanical properties of dental resin composites containing different amounts of microparticulate bioactive glass (BAG). Methods: Experimental resin composites were prepared by mixing resin matrix (70% BisGMA and 30% TEG-DMA) and inorganic filler with various fractions of BAG to achieve final BAG concentrations of 5, 10 and 30 wt%. Antimicrobial efficacy was assessed in aqueous suspension against Escherichia coli, Staphylococcus aureus and Streptococcus mutans and in biofilm against S. mutans. The effect of incorporation of BAG on the mechanical properties of resin composite was evaluated by measuring the surface roughness, compressive strength and flexural strength. Results: Under the dynamic contact condition, viable counts of E. coli, S. aureus and S. mutans in suspensions were reduced up to 78%, 57% and 50%, respectively, after 90 minutes of exposure to disc-shaped composite specimens, depending on the BAG contents. In 2-day-old S. mutans biofilm, incorporation of BAG into composite at ratios of 10% and 30% resulted in 0.8 and 1.4 log reductions in the viable cell counts compared with the BAG-free composite, respectively. The surface roughness values of composite specimens did not show any significant difference (p>0.05) at any concentration of BAG. However, compressive and flexural strengths of composite were decreased significantly with addition of 30% BAG (p<0.05). Conclusions: The results demonstrated the successful utilization of BAG as a promising biomaterial in resin composites to provide antimicrobial function.en_US
dc.identifier.doi10.5301/jabfm.5000271en_US
dc.identifier.endpageE301en_US
dc.identifier.issn2280-8000en_US
dc.identifier.issue3en_US
dc.identifier.pmid27149938en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpageE296en_US
dc.identifier.urihttps://dx.doi.org/10.5301/jabfm.5000271
dc.identifier.urihttps://hdl.handle.net/20.500.12395/33265
dc.identifier.volume14en_US
dc.identifier.wosWOS:000392834300009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWICHTIG PUBLISHINGen_US
dc.relation.ispartofJournal of Applied Biomaterials & Functional Materialsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAntimicrobial efficacyen_US
dc.subjectBioactive glassen_US
dc.subjectBiofilmen_US
dc.subjectMechanical propertiesen_US
dc.subjectResin compositeen_US
dc.titleAntimicrobial and mechanical properties of dental resin composite containing bioactive glassen_US
dc.typeArticleen_US

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