Determination of anae and acp-ase positive lymphocytes of peripheral blood and endometrium tissues in experimental hypothyroidism-ınduced rats

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Küçük Resim

Tarih

2019

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

KAFKAS UNIV, VETERINER FAKULTESI DERGISI

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

This study was aimed to provide information about the status of the immune system by revealing changes in peripheral blood leukocyte (PBL) percentages, ANAE- and ACP-ase(+) lymphocyte rates in peripheral blood (PB) and endometrium tissues of experimental hypothyroidism-induced rats. In this study, 15 healthy female Wistar Albino rats were used. Rats were fed through 4 weeks. The Group E (experimental, n=9) is group that were made hypothyroidism by intraperitoneal methimazole enjection for 2 weeks. Rats of the Group C (control, n=6) were untreated. In the 2nd and 4th weeks, ANAE- and ACP-ase(+) lymphocyte rates of the Group E were higher than Group C in PB. Excepting eosinophil and basophil leukocyte rates, there was no statistical difference in the other PBL percentages in the both of weeks. In PB, while lymphocyte rate of the 4th week was no statistically different (P>0.05), it was found lower in Group C. There was no alteration in ANAE- and ACP-ase(+) lymphocyte rates of uterine tissue. As a result, whereas hypothyroidism caused significant alterations in PBL and T lymphocyte rates, the any marked changes was not observed in the uterine tissue.

Açıklama

Anahtar Kelimeler

ACP-ase, ANAE, Endometrium, Hypothyroidism, Methimazole

Kaynak

KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI

WoS Q Değeri

Q4

Scopus Q Değeri

Q3

Cilt

25

Sayı

2

Künye

Çolakoğlu, F., Dönmez, H. H. (2019). Determination of ANAE and ACP-ase Positive Lymphocytes of Peripheral Blood and Endometrium Tissues in Experimental Hypothyroidism-Induced Rats. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 25(2), 157-162.