Increased ischemia-modified albumin and malondialdehyde levels in videothoracoscopic surgery
dc.contributor.author | Oncel, Muide | |
dc.contributor.author | Kiyici, Aysel | |
dc.contributor.author | Oncel, Murat | |
dc.contributor.author | Sunam, Guven Sadi | |
dc.contributor.author | Sahin, Emel | |
dc.contributor.author | Adam, Bahattin | |
dc.date.accessioned | 2020-03-26T19:24:42Z | |
dc.date.available | 2020-03-26T19:24:42Z | |
dc.date.issued | 2016 | |
dc.department | Selçuk Üniversitesi | en_US |
dc.description.abstract | BACKGROUND: Videothoracoscopic surgery leads to general organ hypoperfusion by reducing mean arterial pressure, systemic vascular resistance, and end-diastolic volume index. Oxidative stress occurs as a result of hypoperfusion. Evaluation of the short-term effects of videothoracoscopic sympathectomy on serum ischemia-modified albumin (IMA), malondialdehyde (MDA), and nitric oxide (NO) levels in patients with primary hyperhidrosis was aimed. METHODS: Twenty-six patients who underwent videothoracoscopic surgery were contributed in this study. Venous blood samples were obtained from these patients 1 h before and after the surgery. IMA, MDA, and NO levels were measured in serum samples by colorimetric methods. Albumin concentrations were also measured for each sample, and albumin-adjusted IMA levels were calculated. RESULTS: Postoperative IMA, albumin-adjusted IMA, and MDA values were significantly higher compared to the preoperative values (P = 0.003, 0.027, 0.018, respectively). However, postoperative NO levels were lower than the preoperative values (P = 0.002). There was no significant difference between pre- and postoperative albumin concentrations, and there was no significant correlation between the parameters tested. CONCLUSIONS: We can conclude that elevation in MDA and IMA levels after videothoracoscopic surgery was caused by increased oxidative stress due to minimal ischemia-reperfusion injury after the infusion of CO 2 during the surgical process. Videothoracoscopic sympathectomy operation causes a decrease in NO production, and this should be taken in consideration when evaluating nitrosative stress in videothoracoscopic surgery. | en_US |
dc.identifier.doi | 10.4103/1817-1737.172298 | en_US |
dc.identifier.endpage | 70 | en_US |
dc.identifier.issn | 1817-1737 | en_US |
dc.identifier.issn | 1998-3557 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.pmid | 26933460 | en_US |
dc.identifier.scopusquality | Q2 | en_US |
dc.identifier.startpage | 66 | en_US |
dc.identifier.uri | https://dx.doi.org/10.4103/1817-1737.172298 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12395/33708 | |
dc.identifier.volume | 11 | en_US |
dc.identifier.wos | WOS:000369748200007 | en_US |
dc.identifier.wosquality | Q3 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.language.iso | en | en_US |
dc.publisher | WOLTERS KLUWER MEDKNOW PUBLICATIONS | en_US |
dc.relation.ispartof | ANNALS OF THORACIC MEDICINE | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.selcuk | 20240510_oaig | en_US |
dc.subject | Ischemia modified albumin | en_US |
dc.subject | malondialdehyde | en_US |
dc.subject | nitric oxide | en_US |
dc.subject | videothoracoscopic surgery | en_US |
dc.title | Increased ischemia-modified albumin and malondialdehyde levels in videothoracoscopic surgery | en_US |
dc.type | Article | en_US |