In Vitro Antimicrobial Activities of Cicer Arietinum L (Chickpea)
Yükleniyor...
Dosyalar
Tarih
2010
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Pharmacotherapy Group
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Purpose: To evaluate the antibacterial and antifungal activities of the extracts of the seed, fruit skin and aerial parts of ten registered varieties of Cicer arietinum (Chickpea) Method: Susceptibility testing was performed according to the Clinical and Laboratory Standards Institute (CLSI) and used an inhibition endpoint for determination of the minimum inhibition concentration (MIC). The tests were carried out by microdilution method against standard strains of E. coli, P. aeruginosa, K. pneumoniae, S. aureus, B. subtilis, and E. faecalis for their antibacterial activity using ampicillin and oflaxocin as reference standards, and against C. albicans with ketocanazole and flukonazole as reference standards for antifungal activity. Results: Chickpea seed extracts (Cse) showed antibacterial activity against Gram-negative strains (E. coli, P. aeruginosa and K. pneumoniae) in the concentration range of 16-64 µg ml but were less active (concentration of 64 µg ml¹) against Gram-positive strains (S. aureus, B. subtilis and E. faecalis). Conclusion: This is the first report showing that C. arietinum extracts has substantial antifungal activity at a concentration as low as 8 µg ml.
Açıklama
Anahtar Kelimeler
Antibacterial, Antifungal, Cicer arietinum, Chickpea
Kaynak
Tropical Journal of Pharmaceutical Research
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
9
Sayı
5
Künye
Kan, A., Özçelik, B., Kartal, M., Özdemir, Z. A., Özgen, S., (2010). In Vitro Antimicrobial Activities of Cicer Arietinum L (Chickpea). Tropical Journal of Pharmaceutical Research, 9(5), 475-481.
