Flexible bronchoscopy may decrease respiratory muscle strength: premedicational midazolam in focus

Basit Öğe Kaydı
dc.contributor.authorTulek, Baykal
dc.contributor.authorKanat, Fikret
dc.contributor.authorTol, Sule
dc.contributor.authorSuerdem, Mecit
dc.date.accessioned2020-03-26T18:30:37Z
dc.date.available2020-03-26T18:30:37Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground: Flexible bronchoscopy (FB) is a procedure accepted to be safe in general, with low complication rates reported. On the other hand, it is known that patients with pre-existing respiratory failure have developed hypoventilation following FB. In this study the effects of FB on respiratory muscle strength were investigated by measuring maximum respiratory pressures. Methods: One hundred and forty patients, aged between 25 and 90 years, who had undergone diagnostic bronchoscopy between February 2012 and May 2012, were recruited to the study. Pre- and post-procedure maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) were measured. A correlation between the MIP and MEP changes and patient characteristics and FB variables were investigated. Results: Significant decreases in both MIP and MEP values were observed following FB (p < 0.001 for both). Decreases were attributed to the midazolam used for sedation. Significant decreases in respiratory muscle strengths were observed especially in the high-dose midazolam group, compared to both low-dose and non-midazolam groups. Conclusions: It was determined that respiratory muscle weakness may arise post-procedure in patients who have undergone FB, and this is constitutively related to midazolam premedication. Respiratory muscle weakness might play a role in potential hypoventilation in critical patients who undergo FB.en_US
dc.identifier.doi10.1186/2049-6958-7-31en_US
dc.identifier.issn2049-6958en_US
dc.identifier.pmid23009348en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://dx.doi.org/10.1186/2049-6958-7-31
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28068
dc.identifier.volume7en_US
dc.identifier.wosWOS:000311990700001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBIOMED CENTRAL LTDen_US
dc.relation.ispartofMULTIDISCIPLINARY RESPIRATORY MEDICINEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectBronchoscopyen_US
dc.subjectMidazolamen_US
dc.subjectRespiratory muscle strengthen_US
dc.titleFlexible bronchoscopy may decrease respiratory muscle strength: premedicational midazolam in focusen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu