The Identification of Genetic Variation in Insulin-Like Growth Factors-I (IGFI) Gene Region in Some Turkish Sheep Breeds

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dc.authorid0000-0002-2085-8632en_US
dc.authorid0000-0001-9358-7522en_US
dc.authorid0000-0002-9248-2056en_US
dc.contributor.authorTawfeeq, Mustafa
dc.contributor.authorKeskin, İsmail
dc.contributor.authorİlhan, Fatma
dc.date.accessioned2023-08-03T09:57:32Z
dc.date.available2023-08-03T09:57:32Z
dc.date.issued2020en_US
dc.departmentSelçuk Üniversitesi, Ziraat Fakültesi, Zootekni Bölümüen_US
dc.description.abstractInsulin-like growth factors (IGFs) areknown as peptides with important metabolic effects required for cellular growth and metabolism. IGF-I is synthesized in liver tissue under the control of growth hormone (GH) and released to blood. In the process of GH to accelerate growth, IGF-I occupies a large place. IGF-I clearly showed its important effects on the growth of animal studies. In this study, promoter region of the IGF-I gene were amplified by polymerase chain reaction (PCR) in sheep breeds (Akkaraman, Kivircik, Awassi, Sakiz, Daglıc, Morkaraman, MalyaKarayaka (15 to 20 sheep per breed)) reared in Turkey. Informative restriction fragment length polymorphisms (RFLPs) were obtained with HaeII enzyme. The digestion of IGF-I gene with HaeII produced two alleles and three genotypes. Genotype frequencies were 59%, 19%and 22% for AA, BB and AB genotypes, respectively. Allele frequencies were 0.70 for A allele and 0.30 for the B allele. This study indicates the genetic profiles of the IGF-1 gene in native Turkish sheep breeds.en_US
dc.identifier.citationTawfeeq, M., Keskin, İ., İlhan, F., (2020). The Identification of Genetic Variation in Insulin-Like Growth Factors-I (IGFI) Gene Region in Some Turkish Sheep Breeds. Selcuk Journal of Agriculture and Food Sciences, 34(3), 189-192. DOI: 10.15316/SJAFS.2020.215en_US
dc.identifier.doi10.15316/SJAFS.2020.215en_US
dc.identifier.endpage192en_US
dc.identifier.issn2458-8377en_US
dc.identifier.issue3en_US
dc.identifier.startpage189en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/49124
dc.identifier.volume34en_US
dc.institutionauthorTawfeeq, Mustafa
dc.institutionauthorKeskin, İsmail
dc.institutionauthorİlhan, Fatma
dc.language.isoenen_US
dc.publisherSelçuk Üniversitesien_US
dc.relation.ispartofSelcuk Journal of Agriculture and Food Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectGrowth hormoneen_US
dc.subjectInsulin-like growth factor (IGF)en_US
dc.subjectSheepen_US
dc.subjectPolymerase chain reaction (PCRen_US
dc.subjectRestriction fragment length polymorphism (RFLP)en_US
dc.subjectSheep breedsen_US
dc.titleThe Identification of Genetic Variation in Insulin-Like Growth Factors-I (IGFI) Gene Region in Some Turkish Sheep Breedsen_US
dc.typeArticleen_US

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