The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extracts

Yükleniyor...
Küçük Resim

Tarih

2019

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

ELSEVIER SCI LTD

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

The main goal of this research was to determine the relationship among chemical structure, bioactivity and temperature of chamomile during subcritical water extraction in isobaric conditions (45 bar) at seven different temperatures (65-210 degrees C). The influence of temperature on phenolic profiles was defined by UHPLC-HESI-MS/MS. The overall results indicate that the presence of conjugated double bonds, side chains, glucose moiety or ether moiety in molecules influence the efficiency of polyphenols' extraction in subcritical water. In terms of antioxidant activity, the extracts were the most active towards ABTS radicals (IC50 = 7.3-16.8 mu g/mL), whereby temperature of 150 degrees C was optimal. On the other hand, the extracts obtained at 115 degrees C showed highest cytotoxicity. Inhibition of alpha-amylase and alpha-glucosidase was the highest at 65 and 85 degrees C, i.e. 0.51 and 4.13 mmolAE/g, respectively. Activity against tyrosinase was the highest at 210 degrees C (17.92 mgKAE/g). The data showed that different non-phenolic compounds may also participate in bio-activities of the extracts.

Açıklama

Anahtar Kelimeler

Subcritical water extraction, Chamomile, UHPLC-HESI-MS/MS, DNA-based sensor, Bioactivity

Kaynak

FOOD CHEMISTRY

WoS Q Değeri

Q1

Scopus Q Değeri

Q1

Cilt

271

Sayı

Künye

Cvetanovic, A., Svarc-Gajic, J., Zekovic, Z., Jerkovic, J., Zengin, G., Gasic, U., Tesic, Z., Mašković, P., Soares, C., Barroso, M. F., Delerue-Matos, C., Đurović, S.(2019). The Influence of the Extraction Temperature on Polyphenolic Profiles and Bioactivity of Chamomile (Matricaria chamomilla L.) Subcritical Water Extracts. Food Chemistry, 271, 328-337.