Treatment with antidepressive drugs improved quality of life in chronic hemodialysis patients

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dc.contributor.authorTürk, S
dc.contributor.authorAtalay, H
dc.contributor.authorAltıntepe, L
dc.contributor.authorGüney, I
dc.contributor.authorOkudan, Nilsel
dc.contributor.authorTonbul, H. Z.
dc.contributor.authorGökbel, Hakkı
dc.date.accessioned2020-03-26T17:04:43Z
dc.date.available2020-03-26T17:04:43Z
dc.date.issued2006
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground: Despite some improvements in dialysis therapies, depression still remains an important problem in chronic hemodialysis (HD) patients. In this study, we aimed to investigate the association of depression and its treatment with quality of life (QOL) in HD patients. Patients and methods: 97 HD patients (52 male, 45 female, mean age 55 16 years) were enrolled. All patients had been dialyzed for more than 6 months. In order to evaluate QOL of the patients, a short form of Medical Outcomes Study (SF-36) was used. Depression was assessed by using Beck Depression Inventory (BDI). Patients who had BDI score >= 15 were diagnosed as to have depression. Patients with depression received antidepressive treatment (sertralin HCl, 50 mg/day) for an 8-week period. After 8-week antidepressive treatment, all biochemical analysis, SF-36 and BDI were performed again. Results: 40 patients (20 male, 20 female, mean age 56 +/- 14 years) had depression. All parameters related to QOL were significantly decreased in patients with depression as compared to patients without depression. Severity of depression was correlated with QOL parameters. After 8 weeks of treatment, as parallel to changes in BDI, QOL parameters improved in patients with depression. Conclusion: Decrease in QOL, associated with depression and antidepressive treatment, improves QOL in HD patients. Hemodialysis patients should be followed-up closely for presence of depression. Treatment of depression with antidepressive drug regimen would lead to relieve the symptoms related to depression,and improvement of QOL in these patients. Antidepressive treatment should be required more often than we prescribe in routine clinical practice now.en_US
dc.identifier.endpage118en_US
dc.identifier.issn0301-0430en_US
dc.identifier.issue2en_US
dc.identifier.pmid16509460en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage113en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/20759
dc.identifier.volume65en_US
dc.identifier.wosWOS:000235192800006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherDUSTRI-VERLAG DR KARL FEISTLEen_US
dc.relation.ispartofCLINICAL NEPHROLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectdepressionen_US
dc.subjectquality of lifeen_US
dc.subjectSF-36en_US
dc.subjectBeck Depression Inventoryen_US
dc.subjectantidepressive treatmenten_US
dc.titleTreatment with antidepressive drugs improved quality of life in chronic hemodialysis patientsen_US
dc.typeArticleen_US

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