Neutrophil elastase levels in periapical exudates of symptomatic and asymptomatic teeth

dc.contributor.authorAlptekin, Nilgün Özlem
dc.contributor.authorArı, Hale
dc.contributor.authorAtaoğlu, Tamer
dc.contributor.authorHaliloğlu, Seyfullah
dc.contributor.authorAlptekin, Tuncay
dc.contributor.authorSerpek, Behiç
dc.date.accessioned2020-03-26T16:57:33Z
dc.date.available2020-03-26T16:57:33Z
dc.date.issued2005
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe aim of this study was to determine neutrophil elastase levels (NE) in periapical exudates and to evaluate its relationship with clinical signs and symptoms of endodontically involved teeth. A total of 42 teeth with periapical periodontitis of 37 patients were clinically examined and spontaneous pain, swelling, pain on palpation or percussion, sinus tract formation and pus discharge were recorded. Additionally, periapical lesion size was measured on periapical radiographs. Periapical exudate samples were obtained during routine root canal treatment by using paper points. Enzyme levels were determined by spectrophotometric assays using the NE specific substrate N-methoxysuccinil-Ala-Ala-Pro-Val-p-nitroanilide. The teeth with signs and symptoms showed higher NE levels than the teeth without symptoms (p < 0.05). The differences were significant when NE levels were presented as total amounts instead of concentration. This study demonstrated that NE in periapical lesions related with clinical symptoms and total enzyme amount may be more reliable mode of data presentation.en_US
dc.identifier.endpage353en_US
dc.identifier.issn0099-2399en_US
dc.identifier.issue5en_US
dc.identifier.pmid15851927en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage350en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/19804
dc.identifier.volume31en_US
dc.identifier.wosWOS:000228761000003en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLIPPINCOTT WILLIAMS & WILKINSen_US
dc.relation.ispartofJOURNAL OF ENDODONTICSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleNeutrophil elastase levels in periapical exudates of symptomatic and asymptomatic teethen_US
dc.typeArticleen_US

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