The effect of systemically administrated zoledronic acid on the osseointegration of dental implants
Yükleniyor...
Dosyalar
Tarih
2012
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
WILEY
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Oral Diseases (2012) 18, 802808 Objective: The aim of conducting this study was to evaluate the effect of zoledronic acid (ZA) on the new bone formation (NBF) after the insertion of a titanium dental implant, which is very popular treatment in dentistry. Study Design: Twelve New Zealand white rabbits were used in this study. The rabbits were divided in two groups. ZA was systemically administered to the study group. Titanium implants were placed to the left and right tibias of the rabbits. Results: The data from the ZA group revealed a statistically significant increase in the bone mineral content and the bone mineral density. A non-decalcified histomorphometric examination conducted on the study group revealed a significant increase of NBF and bone-implant contact (BIC) at 2 and 4 weeks. Conclusion: A single dose of systemic ZA administration increases the rate of NBF and augments the quality of the bone.
Açıklama
Anahtar Kelimeler
dental implant, zoledronic acid, osseointegration, non-decalcified histology
Kaynak
ORAL DISEASES
WoS Q DeÄŸeri
Q1
Scopus Q DeÄŸeri
Q1
Cilt
18
Sayı
8
