Second-to-fourth digit ratio and seborrheic dermatitis in males: A cross-sectional study
Yükleniyor...
Tarih
2019
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Sociedade Brasileira de Dermatologia
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: Seborrheic dermatitis is a common disease characterized by the erythematous plaques with oily-yellow desquamation. Increased sebaceous gland activity by androgenic hormones has played a role in the etiology of the disease. The second-to-fourth digit (2D:4D) ratio is thought to be a marker of prenatal androgen exposure. Objectives: To investigate the association between 2D:4D ratios and seborrheic dermatitis in a male population. Methods: Healthy male controls and patients with seborrheic dermatitis were included in this study. One hundred seborrheic dermatitis patients and 120 healthy controls, aged 17-59, were enrolled. A digital Vernier caliper was used to measure the finger lengths. Seborrheic dermatitis severity was assessed using the Seborrheic Dermatitis Area and Severity Index (SDASI). results: The 2D:4D ratios of the patients (x? = 0.977) were significantly lower than those of the controls (x? = 1.050) for right hands (t = 6.948; p = 0.000; > 0.05). No similar relationship was found between the 2D:4D ratio for left hands (t = 0.901; p = 0.368; > 0.05). Seborrheic dermatitis severity was negatively correlated with 2D:4D ratios of right hands (r = -0.391; p = 0.000-0.05). study liMitations: One of the main limitations of this study was the small sample, which got a head of us from acquiring certain findings about the 2D:4D ratio and seborrheic dermatitis. The other limitation is that the patient selection did not reflect the general population, as a single clinic was studied. conclusion: To the authors’ knowledge, this is the first study examining the relationship between 2D:4D ratios and seborrheic dermatitis. The result of this study may indicate a line of investigation and can support the theory of prenatal androgen exposure. © 2019 by Anais Brasileiros de Dermatologia.
Açıklama
Anahtar Kelimeler
Androgens, Dermatitis, Fingers, Hyperandrogenism, Seborrheic
Kaynak
Anais Brasileiros de Dermatologia
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
94
Sayı
3
Künye
Kaya İslamoğlu, Z. G. (2019). Second-To-Fourth Digit Ratio and Seborrheic Dermatitis in Males: A Cross-Sectional Study. Anais Brasileiros de Dermatologia, 94,(3), 327-330.
