Short-term results of patients with neural tube defects followed-up in the Konya region, Turkey

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dc.contributor.authorYorulmaz, Alaaddin
dc.contributor.authorKonak, Murat
dc.date.accessioned2020-03-26T20:19:17Z
dc.date.available2020-03-26T20:19:17Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground Additional congenital anomalies have often been found in patients with neural tube defect (NTD). We aimed to find out the clinical features, short term prognosis, treatment approaches, and systemic anomalies of NTD patients in the Konya region. Method A total of 186 newborn babies with NTD were retrospectively included in the study and all were assessed in detail for congenital anomalies and clinical features. Results When the application month of the patients was examined, it was seen that the most frequent month was July. Of 186 babies, 101(54.3%) had meningomyelocele, 53 (28.5%) had meningocele, 13 (7.0%) had encephalocele, 16 (8.6%) had spina bifida occulta, and 4 (2.1%) had anencephaly. Of these patients, 97 (52.2%) were male and 89 (47.8%) were female. Hydrocephalus was an almost constant finding and was found in 140 (75.3%) patients. 51 (27.4%) patients had congenital heart disease (CHD). The most common CHD was atrial septal defect 22.3%. Orthopedic anomaly was detected in 51 (27.4%) patients, nephrological anomaly was found in 47 (25.3%) of the cases, congenital hypothyroidism was diagnosed in 14 (7.5%) patients with NTD. The mortality rate of patients diagnosed with NTD was 7.5%. The rates of premature delivery and consanguinity between parents were higher in patients with NTD. Conclusions Our results indicate that at least one congenital anomaly is also present in about two-thirds of newborn babies with NTD, and these anomalies significantly increase their morbidity and mortality. All newborn babies with NTD should be screened for additional congenital anomalies and evaluated with more organized, multidisciplinary methods.en_US
dc.identifier.citationYorulmaz, A., Konak, M. (2019). Short-Term Results Of Patients With Neural Tube Defects Followed-Up İn The Konya Region, Turkey. Bırth Defects Research, 111,(5), 261-269.
dc.identifier.doi10.1002/bdr2.1462en_US
dc.identifier.endpage269en_US
dc.identifier.issn2472-1727en_US
dc.identifier.issue5en_US
dc.identifier.pmid30708397en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage261en_US
dc.identifier.urihttps://dx.doi.org/10.1002/bdr2.1462
dc.identifier.urihttps://hdl.handle.net/20.500.12395/38197
dc.identifier.volume111en_US
dc.identifier.wosWOS:000460569200004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYorulmaz, Alaaddin
dc.institutionauthorKonak, Murat
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofBIRTH DEFECTS RESEARCHen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectcongenital anomaliesen_US
dc.subjectcongenital hypothyroidismen_US
dc.subjectfolic aciden_US
dc.subjecthydrocephalusen_US
dc.subjectneural tube defecten_US
dc.titleShort-term results of patients with neural tube defects followed-up in the Konya region, Turkeyen_US
dc.typeArticleen_US

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