Effect of left bundle branch block on systolic and diastolic function of left ventricle in heart failure

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dc.contributor.authorÖzdemir, Kurtuluş
dc.contributor.authorAltunkeser, Bülent Behlül
dc.contributor.authorKorkut, Bayram
dc.contributor.authorTokaç, Mehmet
dc.contributor.authorGök, Hasan
dc.date.accessioned2020-03-26T16:48:17Z
dc.date.available2020-03-26T16:48:17Z
dc.date.issued2004
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThis study was designed to examine the effect of left bundle branch block (LBBB) on systolic and diastolic function of the left ventricle (LV) in patients with heart failure and in normal subjects. Thirty-six patients with heart failure and LBBB (group 1), 36 patients with heart failure with normal conduction (group 11), and 41 subjects with isolated LBBB (group 111) were compared. Coronary angiography was per-formed and LV end diastolic pressure was calculated. Echocardiography was performed on all patients. LV ejection fraction and mean rate of circumferential shortening were calculated. The following Doppler parameters were evaluated: peak rapid filling velocity (E wave), peak atrial filling velocity (A wave), E- and A-wave integrals, E-wave acceleration time and deceleration time (EDT) and rates (EAR and EDR), the E/A ratio and its integral, and diastolic flow time (DT). The ejection time, isovolumetric relaxation time (IRT), and preejection period were measured using the aortic and mitral flow. LV end diastolic pressure was calculated as 28 +/- 4 mm Hg, 22 +/- 5 mm Hg, and 15 +/- 3 mm Hg in groups 1, 11, and III, respectively. Although the systolic function parameters in group III patients were different, the diastolic function parameters of group 11 were found to be quite similar to those of group III patients. Comparison of group I patients with group 11 patients showed that there was a similarity between LV systolic function parameters while the diastolic function parameters were different (E/A, p = 0.004; EAR, p < 0.001; EDR, p < 0.001; EDT, p < 0.001; IRT, p = 0.024; DT, p = 0.03). In conclusion, this study evaluating the effects of LBBB in normal subjects (isolated LBBB) and patients with heart failure showed that LBBB causes diastolic function impairment in normal subjects similar to those of patients with heart failure, and also increases impairment of diastolic function in patients with heart failure.en_US
dc.identifier.doi10.1177/000331970405500109en_US
dc.identifier.endpage71en_US
dc.identifier.issn0003-3197en_US
dc.identifier.issn1940-1574en_US
dc.identifier.issue1en_US
dc.identifier.pmid14759091en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage63en_US
dc.identifier.urihttps://dx.doi.org/10.1177/000331970405500109
dc.identifier.urihttps://hdl.handle.net/20.500.12395/19013
dc.identifier.volume55en_US
dc.identifier.wosWOS:000188084600009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSAGE PUBLICATIONS INCen_US
dc.relation.ispartofANGIOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleEffect of left bundle branch block on systolic and diastolic function of left ventricle in heart failureen_US
dc.typeArticleen_US

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