Left ventricular diastolic function evaluated with tissue Doppler imaging in children with familial Mediterranean fever

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dc.contributor.authorBaysal, Tamer
dc.contributor.authorPeru, Harun
dc.contributor.authorOran, Bulent
dc.contributor.authorSahin, Tahir Kemal
dc.contributor.authorKoksal, Yavuz
dc.contributor.authorKaraaslan, Sevim
dc.date.accessioned2020-03-26T17:39:07Z
dc.date.available2020-03-26T17:39:07Z
dc.date.issued2009
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe aim of this study was to assess the left ventricular diastolic function using conventional echocardiography and tissue Doppler imaging in children with familial Mediterranean fever. This study included 29 (13 males and 16 females) patients and 30 healthy subjects as controls. Body mass index was calculated and arterial blood pressure was monitored. After an overnight fast, venous blood samples were taken and serum amyloid A protein, C-reactive protein, serum-fasting glucose, total cholesterol, triglycerides, high-density lipoprotein cholesterol, very low density lipoprotein cholesterol, and serum low-density lipoprotein cholesterol levels were measured. A complete 2-dimensional, M-mode, pulse wave Doppler, and pulse wave tissue Doppler echocardiographic examination was performed. There were no significant differences between the groups regarding age, body mass index values, systolic and diastolic blood pressures, heart rates, serum-fasting glucose, total cholesterol, triglycerides, high-density lipoprotein cholesterol, very low density lipoprotein cholesterol, and serum low-density lipoprotein cholesterol. Serum levels of inflammatory markers were higher in patients' group (C-reactive protein and serum amyloid A protein levels were 10.84 mg/dl, 22.32 mg/l in patients' group, respectively, and 4.11 mg/dl, 3.65 mg/l, respectively, in the healthy controls.) Peak mitral A wave, E and A wave ratio differed significantly in both groups. There were statistically significant differences regarding parameters observed by tissue Doppler imaging such as E'm, A'm, E'm, and A'm ratio between patients' group and controls. Tissue Doppler imaging provided additional information on left ventricular diastolic function. While systolic functions were in normal range, some of the diastolic function parameters were impaired in patients with familial Mediterranean fever during childhood.en_US
dc.identifier.doi10.1007/s10067-008-0976-zen_US
dc.identifier.endpage28en_US
dc.identifier.issn0770-3198en_US
dc.identifier.issn1434-9949en_US
dc.identifier.issue1en_US
dc.identifier.pmid18716732en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage23en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s10067-008-0976-z
dc.identifier.urihttps://hdl.handle.net/20.500.12395/23649
dc.identifier.volume28en_US
dc.identifier.wosWOS:000261185900004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSPRINGER LONDON LTDen_US
dc.relation.ispartofCLINICAL RHEUMATOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectChildrenen_US
dc.subjectFamilial Mediterranean feveren_US
dc.subjectTissue Doppler imagingen_US
dc.titleLeft ventricular diastolic function evaluated with tissue Doppler imaging in children with familial Mediterranean feveren_US
dc.typeArticleen_US

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