The Effect of Testosterone Used in Sportsmen on Routine Biochemical Parameters
Yükleniyor...
Dosyalar
Tarih
2010
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
MEDWELL ONLINE
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The purpose of the research was to determine indicators of testosterone implication on heart, liver and kidney failure in female rats during puberty and also to determine its effect on some other chemical values. In the research, female 16 Sprague dawley rats (50 days) were used. The rats were divided into two equal groups. The first group was administrated testosterone, diluted with olive oil, 5 mg kg(-1) (SID) subcutaneously for 10 weeks, 5 days each week. The second group was only given olive oil. Serum creatine kinase, creatine kinase-MB, alkaline phosphates, alanine aminotransferase, aspartate aminotransferase, blood urea nitrogen, creatinine, triglyceride, cholesterol, high density lipoprotein, amylase, total protein, albumin and calcium were measured with an auto-analyzer. It was determined that while testosterone application in female rats leads to decrease on the total serum protein and albumin levels (p<0.05), it increased aspartate aminotransferase and cholesterol levels (p<0.05). Consequently, it can be stated that long term testosterone implication during puberty may lead to organ defects at early ages.
Açıklama
Anahtar Kelimeler
Testosterone, Cholesterol, Aspartate Aminotransferase, Total Protein, Albumin, Turkey
Kaynak
Journal of Animal and Veterinary Advances
WoS Q Değeri
Q3
Scopus Q Değeri
N/A
Cilt
9
Sayı
15
Künye
Taşgın, E., Lok, S., Demir, N., Özdemir, M., (2010). The Effect of Testosterone Used in Sportsmen on Routine Biochemical Parameters. Journal of Animal and Veterinary Advances, 9(15), 2038-2040.