Quercetin and caffeic acid phenethyl ester (CAPE) attenuate acute exercise-induced oxidative stress

Küçük Resim Yok

Tarih

2015

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

MATTIOLI 1885

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Flavonoids are naturally occurring antioxidant molecules that are abundantly existing in the human diet. We investigated effects of quercetin and caffeic acid phenethyl ester to redox balance in acute treadmill exercise. Malondialdehyde, superoxide dismutase activity, xanthine oxidase activity and total nitrite in blood, skeletal muscle and liver were analyzed in 58 male Sprague-Dawley rats that were exposed to a single bout of exercise. We found that exercise provoked the increment of analyzed parameters except for total nitrite which indicates nitric oxide. Quercetin and caffeic acid phenethyl ester decreased malondialdehyde levels in skeletal muscle and liver. However, they were ineffectual in preventing lipid peroxidation in blood probably due to limited repair and biosynthesis capability of erythrocytes. Since quercetin and CAPE successfully weakened oxidative stress in liver and skeletal muscle, they may be seen as promising in preventing acute exercise-induced oxidative injury.

Açıklama

Anahtar Kelimeler

Oxidative stress, quercetin, caffeic acid phenethyl ester, CAPE, acute exercise

Kaynak

PROGRESS IN NUTRITION

WoS Q Değeri

Q4

Scopus Q Değeri

Q4

Cilt

17

Sayı

1

Künye