Quercetin and caffeic acid phenethyl ester (CAPE) attenuate acute exercise-induced oxidative stress

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dc.contributor.authorGergerlioglu, Hasan Serdar
dc.contributor.authorGokbel, Hakki
dc.contributor.authorOkudan, Nilsel
dc.contributor.authorGergerlioglu, Nursadan
dc.contributor.authorDemir, Enver Ahmet
dc.date.accessioned2020-03-26T19:06:51Z
dc.date.available2020-03-26T19:06:51Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractFlavonoids are naturally occurring antioxidant molecules that are abundantly existing in the human diet. We investigated effects of quercetin and caffeic acid phenethyl ester to redox balance in acute treadmill exercise. Malondialdehyde, superoxide dismutase activity, xanthine oxidase activity and total nitrite in blood, skeletal muscle and liver were analyzed in 58 male Sprague-Dawley rats that were exposed to a single bout of exercise. We found that exercise provoked the increment of analyzed parameters except for total nitrite which indicates nitric oxide. Quercetin and caffeic acid phenethyl ester decreased malondialdehyde levels in skeletal muscle and liver. However, they were ineffectual in preventing lipid peroxidation in blood probably due to limited repair and biosynthesis capability of erythrocytes. Since quercetin and CAPE successfully weakened oxidative stress in liver and skeletal muscle, they may be seen as promising in preventing acute exercise-induced oxidative injury.en_US
dc.description.sponsorshipSelcuk University Scientific Research Projects Coordination UnitSelcuk University [08401101]en_US
dc.description.sponsorshipThis research is granted by Selcuk University Scientific Research Projects Coordination Unit (project no: 08401101). We gratefully acknowledge the kind help of Sadik Buyukbas, M.D., Cigdem Dolek, Ph.D., Mustafa Kemal Basarali, M.D., Ph.D, Mehmet Oz, Ph.D.en_US
dc.identifier.endpage49en_US
dc.identifier.issn1129-8723en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage41en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/32488
dc.identifier.volume17en_US
dc.identifier.wosWOS:000351114900005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherMATTIOLI 1885en_US
dc.relation.ispartofPROGRESS IN NUTRITIONen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectOxidative stressen_US
dc.subjectquercetinen_US
dc.subjectcaffeic acid phenethyl esteren_US
dc.subjectCAPEen_US
dc.subjectacute exerciseen_US
dc.titleQuercetin and caffeic acid phenethyl ester (CAPE) attenuate acute exercise-induced oxidative stressen_US
dc.typeArticleen_US

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