The Role of Prohepcidin and Hepcidin in Anemia Associated with Behcet's Disease

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dc.contributor.authorDağlı, Mehmet
dc.contributor.authorYılmaz, Sema
dc.contributor.authorSivrikaya, Abdullah
dc.contributor.authorÇelik, Gülperi
dc.date.accessioned2020-03-26T18:31:53Z
dc.date.available2020-03-26T18:31:53Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe aim of the study is to investigate the role of circulating prohepcidin and hepcidin, which are homeostatic regulators of iron metabolism and mediators of inflammation, in anemia associated with Behcet's disease (BD) and the differential diagnosis of healthy controls. Twenty patients with BD and twenty healthy controls were included in this prospective study. Laboratory tests including. complete blood count, serum prohepcidin, hepcidin, iron, total iron binding capacity (TIBC), transferrin, ferritin, erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were determined. Serum prohepcidin and hepcidin levels in patients with BD were significantly higher than healthy group. In the group with BD positive correlation was determined between the values of serum prohepcidin, hepcidin, hemoglobin, total binding capacity and ferritine. Serum prohepcidin and hepcidin levels are closely associated with disease activity in patients and might play a role in the pathobiology of chronic disease anemia associated with patients with BD.en_US
dc.identifier.citationDağlı, M., Yılmaz, S., Sivrikaya, A., Çelik, G., (2012). The Role of Prohepcidin and Hepcidin in Anemia Associated with Behcet's Disease. Uhod-Uluslararasi Hematoloji-Onkoloji Dergisi, 22(2), 94-98. DOI: 10.4999/uhod.11025
dc.identifier.doi10.4999/uhod.11025en_US
dc.identifier.endpage98en_US
dc.identifier.issn1306-133Xen_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage94en_US
dc.identifier.urihttps://dx.doi.org/10.4999/uhod.11025
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28564
dc.identifier.volume22en_US
dc.identifier.wosWOS:000306389300005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorDağlı, Mehmet
dc.institutionauthorYılmaz, Sema
dc.institutionauthorSivrikaya, Abdullah
dc.institutionauthorÇelik, Gülperi
dc.language.isoenen_US
dc.publisherAKAD DOKTORLAR YAYINEVIen_US
dc.relation.ispartofUhod-Uluslararasi Hematoloji-Onkoloji Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectProhepcidinen_US
dc.subjectHepcidinen_US
dc.subjectAnemiaen_US
dc.subjectBehçet's Diseaseen_US
dc.titleThe Role of Prohepcidin and Hepcidin in Anemia Associated with Behcet's Diseaseen_US
dc.typeArticleen_US

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