Effects of isoflurane and sevoflurane on the survival of skin flaps in rats

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dc.contributor.authorTosun, Z
dc.contributor.authorTuncer, S
dc.contributor.authorYosunkaya, A
dc.contributor.authorOzkan, A
dc.contributor.authorSenturk, S
dc.contributor.authorSavaci, N
dc.date.accessioned2020-03-26T16:57:03Z
dc.date.available2020-03-26T16:57:03Z
dc.date.issued2005
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe effects of inhalational anaesthetic agents on survival of flaps are not well known. We investigated the effect of isoflurane and sevoflurane anaesthesia on survival of flaps using a caudally-based McFarlane skin flap in 20 male Wistar rats. Sevoflurane 1 minimum alveolar concentration (MAC) and isoflurane (1 MAC) in oxygen mixture was given to the animals. A 4 x 10 cm caudally-based standard McFarlane flap was raised. There were no differences in any haemodynamic values or blood gases between the sevoflurane group and the isoflurane group. Skin flaps were assessed on the seventh day. The isoflurane group had a significantly smaller area of skin flap necrosis and an increased area of flap surviving than the sevoflurane group. We conclude that survival is significantly improved when isoflurane is used as the inhalational anaesthetic rather than sevoflurane.en_US
dc.identifier.doi10.1080/0284431051006312en_US
dc.identifier.endpage271en_US
dc.identifier.issn0284-4311en_US
dc.identifier.issue5en_US
dc.identifier.pmid16320401en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage268en_US
dc.identifier.urihttps://dx.doi.org/10.1080/0284431051006312
dc.identifier.urihttps://hdl.handle.net/20.500.12395/19707
dc.identifier.volume39en_US
dc.identifier.wosWOS:000232727700003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS ASen_US
dc.relation.ispartofSCANDINAVIAN JOURNAL OF PLASTIC AND RECONSTRUCTIVE SURGERY AND HAND SURGERYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectflap survivalen_US
dc.subjectisofluraneen_US
dc.subjectsevofluraneen_US
dc.titleEffects of isoflurane and sevoflurane on the survival of skin flaps in ratsen_US
dc.typeArticleen_US

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