Gastric Emptying in Subclinical Hyperthyroidism

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Küçük Resim

Tarih

2003

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Maghira & Maas Publications

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

INTRODUCTION AND AIM: About 15% of hyperthyroid patients suffer from gastrointestinal symptoms such as diarrhea, constipation, nausea and early satiety the problem. Published reports on the topic of gastric emptying in hyperthyroidism are rare and discrepant in their results. PATIENTS AND M ETHODS: Thirteen patients (8 women, 5 male; aged 41.92+/-1.491 SE yr) with a recently established diagnosis of subclinical hyperthyroidism due to Graves-Basedow disease and as control group 10 age-matched healthy subject (7 women, 3 male; 39.6+/-2.918 SE yrs) participated in this study. Scintigraphic method (food labeled with Tc-99m sulfur colloid) was used for measurement of gastric emptying. RESULTS: Gastric emptying time was similar in both subclinical hyperthyroid and control groups (p=0.413). DISCUSSION: There are few studies on the subject of gastric emptying in hyperthyroidism with either delayed emptying or with emptying time similar to controls. In the only one study in subclinical hyperthyroidism, gastric emptying was found to be delayed. We also found that gastric emptying was delayed in subclinical hyperthyroidism. On the basis of this and other studies, we may suggest that in subclinical hyperthyroidism, gastric emptying of solids were similar to that in age-matched healthy control subjects and gastrointestinal dysfunction is dependent on severity of the hyperthyroid state and might be a result of impaired neuro-hormonal regulation. Yet the data must be supported on larger groups.

Açıklama

Anahtar Kelimeler

Subclinical hyperthyroidism, Gastric emptying, Tc-99m sulfur colloid

Kaynak

Neuroendocrinology Letters

WoS Q Değeri

Q3

Scopus Q Değeri

Q4

Cilt

24

Sayı

3-4

Künye

Kısakol, G., Kayaçetin, E., Sarı, O., Kaya, A., (2003). Gastric Emptying in Subclinical Hyperthyroidism. Neuroendocrinology Letters, 24(3-4), 255-258.