P-wave duration and dispersion in children with uncomplicated familial Mediterranean fever

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dc.contributor.authorArslan, Derya
dc.contributor.authorOran, Bulent
dc.contributor.authorYazilitas, Fatma
dc.contributor.authorPeru, Harun
dc.contributor.authorCimen, Derya
dc.contributor.authorVatansev, Husamettin
dc.date.accessioned2020-03-26T18:43:04Z
dc.date.available2020-03-26T18:43:04Z
dc.date.issued2013
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjectives This was a prospective controlled study to determine the P-wave duration (Pdu) and P-wave dispersion (Pd) in patients with familial Mediterranean fever (FMF). Methods The study group consisted of 26 children with uncomplicated FMF and 25 age-and sex-matched healthy controls. We performed electrocardiography (ECG) with Doppler echocardiography on patients and controls. All participants underwent 12-lead electrocardiography under strict standards. Pdu and Pd were computed from a randomly selected beat and from an averaged beat constructed from 12 beats, included in a 10-s ECG. Results The left ventricle (LV) dimensions, LV ejection fraction (LVEF), and LV fractional shortening (LVFS) values, left atrium dimension, and aortic dimension were in normal range in both groups. There were significant differences between the groups regarding LV-isovolumic relaxation time (IRT), LV-isovolumic contraction time (ICT), right ventricle (RV)-ICT, RV-IRT, and Pd (all p < 0.0001). However, highly significant positive correlation was detected between LV-ICT, LV-IRT, RV-ICT, RV-IVT, C-reactive protein (CRP), and Pd (r = 0.505, p < 0.0001; r = 0.483, p < 0.0001; r = 0.433, p = 0.001; r = 0.421, p = 0.001; r = 0.452, p = 0.001; r = 0.478, p < 0.0001, respectively). Conclusions Uncomplicated FMF children who are continuously treated with colchicine and do not develop amyloidosis have abnormal atrial dispersion and therefore seemingly have an increased electrocardiographic risk of atrial fibrillation.en_US
dc.identifier.doi10.3109/s10165-012-0815-6en_US
dc.identifier.endpage1171en_US
dc.identifier.issn1439-7595en_US
dc.identifier.issn1439-7609en_US
dc.identifier.issue6en_US
dc.identifier.pmid23274952en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1166en_US
dc.identifier.urihttps://dx.doi.org/10.3109/s10165-012-0815-6
dc.identifier.urihttps://hdl.handle.net/20.500.12395/29762
dc.identifier.volume23en_US
dc.identifier.wosWOS:000328090100017en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS LTDen_US
dc.relation.ispartofMODERN RHEUMATOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAtrial fibrillationen_US
dc.subjectDoppler echocardiographyen_US
dc.subjectFamilial Mediterranean feveren_US
dc.subjectP-wave dispersionen_US
dc.titleP-wave duration and dispersion in children with uncomplicated familial Mediterranean feveren_US
dc.typeArticleen_US

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