The molecular pathogenesis and management of bronchial carcinoids

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dc.contributor.authorCakir, Mehtap
dc.contributor.authorGrossman, Ashley
dc.date.accessioned2020-03-26T18:17:02Z
dc.date.available2020-03-26T18:17:02Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAreas covered: The molecular biology and novel molecular pathways and drug targets in bronchial carcinoids are reviewed in this paper. A full data search is performed through PubMed over the years 2000 -- 2010 with key words ''neuroendocrine tumors of the lung, bronchial carcinoid, lung carcinoid, foregut carcinoid, pulmonary carcinoid, pulmonary NETs, lung NETs, molecular biology, autoradiography, nuclear medicine, treatment''; all relevant publications are included, together with selected publications prior to that date. Expert opinion: Although lying at the benign end of the spectrum of pulmonary NETs, bronchial carcinoids can metastasize, and the pathogenesis of these tumors is poorly understood. Several intracellular signaling pathways are under investigation to define new targets for the successful treatment of these tumors. In terms of treatment, further research should additionally focus on the already known but promising drug options.en_US
dc.identifier.doi10.1517/14728222.2011.555403en_US
dc.identifier.endpage491en_US
dc.identifier.issn1472-8222en_US
dc.identifier.issn1744-7631en_US
dc.identifier.issue4en_US
dc.identifier.pmid21275849en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage457en_US
dc.identifier.urihttps://dx.doi.org/10.1517/14728222.2011.555403
dc.identifier.urihttps://hdl.handle.net/20.500.12395/26968
dc.identifier.volume15en_US
dc.identifier.wosWOS:000288170100007en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS LTDen_US
dc.relation.ispartofEXPERT OPINION ON THERAPEUTIC TARGETSen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectbronchial carcinoiden_US
dc.subjectmolecular biologyen_US
dc.subjectneuroendocrine tumoren_US
dc.subjecttreatmenten_US
dc.titleThe molecular pathogenesis and management of bronchial carcinoidsen_US
dc.typeReviewen_US

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