Effect of Tilmicosin on Serum Creatine Kinase, Creatine Kinase-MB and Troponin I Levels in New Zealand White Rabbits

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Tarih

2002

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Eugen Ulmer Gmbh CO

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

In this study, the effect of tilmicosin on creatine kinase, creatine kinase-MB and troponin I levels were investigated to determine the possible cardiotoxic effect. Ten male White New Zealand rabbits were used as materials and tilmicosin was injected at a dose of 25 mg/kg body weight, subcutanously, by single injection. Blood samples were taken before the injection (=control) and at 6 hours after injection. Tilmicosin caused increases in creatine kinase, creatine kinase-MB and troponin I levels. However, especially histopathological examinations have to be made for fully determination of tilmicosin cardiotoxicity in rabbits.

Açıklama

Anahtar Kelimeler

rabbit, tilmicosin, blood serum, creatine kinase, creatine kinase-MB, troponin I

Kaynak

Archiv Fur Geflugelkunde

WoS Q Değeri

Q4

Scopus Q Değeri

N/A

Cilt

66

Sayı

5

Künye

Yazar, E., Birdane, Y. O., Elmas, M., Traş, B., Baş, A. L., (2002). Effect of Tilmicosin on Serum Creatine Kinase, Creatine Kinase-MB and Troponin I Levels in New Zealand White Rabbits. Archiv Fur Geflugelkunde, 66(5), 237-239.