The evaluation of coagulation profiles in calves with suspected septic shock

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dc.contributor.authorIrmak, K
dc.contributor.authorSen, I
dc.contributor.authorCol, R
dc.contributor.authorBirdane, FM
dc.contributor.authorGuzelbektes, H
dc.contributor.authorCivelek, T
dc.contributor.authorYilmaz, A
dc.date.accessioned2020-03-26T17:04:34Z
dc.date.available2020-03-26T17:04:34Z
dc.date.issued2006
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe purpose of the study reported here was to evaluate the haemostatic function in calves with suspected septic shock and to reflect the occurrence of disseminated intravascular coagulation (DIC). Twenty-six calves suspected of having septic shock (experimental group) and 10 clinically healthy calves (control group) were used. On admission, the experimental group of calves had been ill for an average of 2 days. Therapy was applied to the experimental group of calves. The packed cell volume (PCV), haemoglobin (Hb), white blood cell (WBC), red blood cell (RBC) and platelet (PLT) counts were determined. Blood smears for toxic neutrophil and schistocyte intensity were evaluated. For the coagulation profile, plasma activated partial thromboplastin time (APTT), prothrombin time (PT), thrombin time (TT), fibrinogen and fibrin/fibrinogen degradation products (FDPs) values were determined. Toxic neutrophils in blood smears were observed in 12 calves of the experimental group. APTT was prolonged in the experimental group compared with the control group (p < 0.05). Fibrinogen concentration was found to be higher in the experimental group than in the control group (p < 0.001). Total leukocyte counts were higher in the experimental group compared with the control group (p < 0.01). Platelet counts in the experimental group were lower than the control group (p < 0.001). However, when the individual values of coagulation profiles of each calf were evaluated, 8 calves had at least three abnormal coagulation profiles (APTT > 72 s, PT > 34.5 s, TT > 33.7 s, FDPs > 5 mu g/ml, PLT <= 150 x 10(3)/mm(3)) and abnormal erythrocyte morphology (schistocytes >= 1). The most common abnormal tests in the coagulation profile were APTT and PT (7 cases), FDPs (6 cases), thrombocytopenia (4 cases), and schistocytes in blood smears (8 cases) in these 8 calves. The results of this study indicate that DIC might be a significant risk factor for mortality in calves with suspected septic shock.en_US
dc.identifier.doi10.1007/s11259-006-3258-8en_US
dc.identifier.endpage503en_US
dc.identifier.issn0165-7380en_US
dc.identifier.issue5en_US
dc.identifier.pmid16755361en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage497en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s11259-006-3258-8
dc.identifier.urihttps://hdl.handle.net/20.500.12395/20729
dc.identifier.volume30en_US
dc.identifier.wosWOS:000238099700004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSPRINGERen_US
dc.relation.ispartofVETERINARY RESEARCH COMMUNICATIONSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectseptic shocken_US
dc.subjectcalvesen_US
dc.subjectDICen_US
dc.titleThe evaluation of coagulation profiles in calves with suspected septic shocken_US
dc.typeArticleen_US

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