Prospective Assessment of Quality of Life and Psychological Distress in Patients With Gynecologic Malignancy A 1-Year Prospective Study

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dc.contributor.authorYavas, Guler
dc.contributor.authorDogan, Nasuh Utku
dc.contributor.authorYavas, Cagdas
dc.contributor.authorBenzer, Nilgun
dc.contributor.authorYuce, Deniz
dc.contributor.authorCelik, Cetin
dc.date.accessioned2020-03-26T18:31:08Z
dc.date.available2020-03-26T18:31:08Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: Our aim was to evaluate the health-related quality of life (HRQoL) and psychological distress in patients treated with radiotherapy (RT) for gynecologic malignancy. Methods: Fifty-seven women with either cervical or endometrial cancer were prospectively enrolled. We assessed HRQoL at baseline (after surgery before RT), at the end of RT, and during follow-up (every 3 months thereafter) using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire 30 (EORTC QLQ-C30), European Organization for Research and Treatment of Cervical Cancer Quality of Life Questionnaire 24 (EORTC QLQ-CX24), and Hospital Anxiety and Depression Scale. Results: We demonstrated changes in appetite loss (P = 0.03), nausea and vomiting (P = 0.02), and role function score (P = 0.003) domains of EORTC QLQ-C30. Only the mean body image score of EORTC QLQ-CX24 was significantly different during follow-up (P = 0.02). Type of surgery, histopathological diagnosis, and the menopausal and marital status of the patients affected baseline body image scores (P = 0.032, 0.004, and 0.019 and 0.005, respectively). Patients who underwent chemotherapy had higher baseline body image scores when compared with patients without any chemotherapy before RT (P = 0.028). All the complaints of patients except body image scores improved during the follow-up period. The baseline and follow-up anxiety and depression scores did not differ significantly. Conclusions: Although pelvic RT deteriorated HRQoL in gynecologic cancer, patients' improvement in HRQoL during follow-up was observed. Patients receiving RT could be reassured about the improvement of acute adverse effects in the course of treatment.en_US
dc.identifier.doi10.1097/IGC.0b013e3182559c03en_US
dc.identifier.endpage1101en_US
dc.identifier.issn1048-891Xen_US
dc.identifier.issue6en_US
dc.identifier.pmid22672986en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1096en_US
dc.identifier.urihttps://dx.doi.org/10.1097/IGC.0b013e3182559c03
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28340
dc.identifier.volume22en_US
dc.identifier.wosWOS:000305908800030en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLIPPINCOTT WILLIAMS & WILKINSen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCERen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectHealth-related quality of lifeen_US
dc.subjectGynecological malignancyen_US
dc.subjectPsychological distressen_US
dc.subjectRadiotherapyen_US
dc.titleProspective Assessment of Quality of Life and Psychological Distress in Patients With Gynecologic Malignancy A 1-Year Prospective Studyen_US
dc.typeArticleen_US

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