The Effect of Antenatal Steroids on Fetal Lung Maturation between the 34th and 36th Week of Pregnancy

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dc.contributor.authorBalcı, Osman
dc.contributor.authorÖzdemir, Suna
dc.contributor.authorMahmoud, Alaa S.
dc.contributor.authorAcar, Ali
dc.contributor.authorÇolakoğlu, Mehmet C.
dc.date.accessioned2020-03-26T18:05:11Z
dc.date.available2020-03-26T18:05:11Z
dc.date.issued2010
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAim: To evaluate the effect of antenatal treatment with a single dose of betamethasone between the 34th and the 36th week of pregnancy on the maturation of fetal lung. Methods: To study 100 pregnant women in their 34th-36th week of pregnancy who were diagnosed as susceptible to have preterm delivery. Fifty patients did not receive betamethasone (group 1). The other 50 patients were administered 12 mg betamethasone in a single dose (group 2). Patients who delivered at least 24 h after the administration of betamethasone were included in this study. After delivery, the Apgar score and the development of respiratory distress syndrome (RDS) in the neonates were compared. Results: Group 2 babies had better Apgar scores when compared to group 1, and the difference was statistically significant. Sixteen (32%) neonates of group 1 and 7 (14%) neonates of group 2 required resuscitation, and the difference was statistically significant (p = 0.032; OR = 0.34, 95% CI 0.12-0.93). RDS was detected in 8 newborns of group 1 and 2 of group 2. The difference was statistically significant (p = 0.046; OR = 0.21, 95% CI 0.04-1.08). Conclusion: The administration of a single dose of betamethasone to pregnant women in their 34th-36th week of pregnancy who are likely to have preterm delivery reduces RDS development. There is a need for larger studies to confirm these results.en_US
dc.identifier.citationBalcı, O., Özdemir, S., Mahmoud, A. S., Acar, A., Çolakoğlu, M. C., (2010). The Effect of Antenatal Steroids on Fetal Lung Maturation between the 34th and 36th Week of Pregnancy. Gynecologic and Obstetric Investigation, 70(2), 95-99. DOI: 10.1159/000295898
dc.identifier.doi10.1159/000295898en_US
dc.identifier.endpage99en_US
dc.identifier.issn0378-7346en_US
dc.identifier.issn1423-002Xen_US
dc.identifier.issue2en_US
dc.identifier.pmid20234136en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage95en_US
dc.identifier.urihttps://dx.doi.org/10.1159/000295898
dc.identifier.urihttps://hdl.handle.net/20.500.12395/25336
dc.identifier.volume70en_US
dc.identifier.wosWOS:000279593400006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBalcı, Osman
dc.institutionauthorÖzdemir, Suna
dc.institutionauthorMahmoud, Alaa S.
dc.institutionauthorAcar, Ali
dc.institutionauthorÇolakoğlu, Mehmet C.
dc.language.isoenen_US
dc.publisherKARGERen_US
dc.relation.ispartofGynecologic and Obstetric Investigationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectFetal Lung Maturationen_US
dc.subjectBetamethasoneen_US
dc.subjectRespiratory Distress Syndromeen_US
dc.titleThe Effect of Antenatal Steroids on Fetal Lung Maturation between the 34th and 36th Week of Pregnancyen_US
dc.typeArticleen_US

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