Cytomorphometric Characteristics of Buccal Mucosal Cells in Behcet's Disease Patients

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dc.contributor.authorAktunç, Erol
dc.contributor.authorÖz, Zehra Safi
dc.contributor.authorBektaş, Sibel
dc.contributor.authorAltınyazar, Cevdet
dc.contributor.authorKoca, Rafet
dc.contributor.authorBostan, Serdar
dc.date.accessioned2020-03-26T19:23:30Z
dc.date.available2020-03-26T19:23:30Z
dc.date.issued2016
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground. The aim of this study was to compare the cytomorphometric characteristics of the buccal cells of Behccet's disease patients with those of healthy controls. Methods. This case-control study compared a group of 30 patients with Behcet's disease with an age-and gender-matched control group of 30 healthy individuals. The buccal mucosal smears were stained using the Papanicolaou technique for cytomorphometric analyses. The nuclear and cytoplasmic areas were evaluated using digital image analysis; the ratio of nuclear to cytoplasmic areas and nuclear roundness are presented. Results. The nuclear and cytoplasmic areas of the BD patients' cells were significantly smaller than those of the healthy controls' cells, while the nucleus-to-cytoplasm ratio and neutrophil infiltration rate did not differ significantly between the groups. However, the nuclear area, cytoplasmic area, nucleus-to-cytoplasm ratio, and nuclear roundness factor were significantly higher in patients without aphthae. The neutrophil infiltration rate did not differ significantly in patients with or without aphthae. Conclusion. Behcet's disease can produce cytomorphometric changes in buccal cells that are detectable by exfoliative cytology and cytomorphometric analysis techniques.en_US
dc.identifier.doi10.1155/2016/6035801en_US
dc.identifier.issn2210-7177en_US
dc.identifier.issn2210-7185en_US
dc.identifier.pmid27088074en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://dx.doi.org/10.1155/2016/6035801
dc.identifier.urihttps://hdl.handle.net/20.500.12395/33413
dc.identifier.wosWOS:000373634600001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHINDAWI LTDen_US
dc.relation.ispartofANALYTICAL CELLULAR PATHOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleCytomorphometric Characteristics of Buccal Mucosal Cells in Behcet's Disease Patientsen_US
dc.typeArticleen_US

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