Does Mild Renal Failure Affect Coronary Flow Reserve after Coronary Artery Bypass Graft Surgery?

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dc.contributor.authorGunday, Murat
dc.contributor.authorCiftci, Ozgur
dc.contributor.authorCaliskan, Mustafa
dc.contributor.authorOzulku, Mehmet
dc.contributor.authorBingol, Hakan
dc.contributor.authorKorez, Kazim
dc.contributor.authorAslamaci, Sait
dc.date.accessioned2020-03-26T18:50:08Z
dc.date.available2020-03-26T18:50:08Z
dc.date.issued2014
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIntroduction: There are only a limited number of studies on the link between mild renal failure and coronary artery disease. The purpose of this study is to investigate the effects of mild renal failure on the distal vascular bed by measuring the coronary flow reserve (CFR) in transthoracic echocardiography after coronary artery bypass grafting (CABG). Methods: The study included 52 consecutive patients (12 women and 40 men) who had undergone uncomplicated CABG. The patients were divided into 2 groups. Group 1 included patients with a preoperative glomerular filtration rate (GFR) of 60-90 (mild renal failure), and group 2 included those with a GFR > 90. The CFR measurements were carried out through a second harmonic transthoracic Doppler echocardiography. Results: The mean age was 60.08 +/- 1.56 years in group 1 and 60.33 +/- 1.19 in group 2. The mean preoperative CFR was 1.79 +/- 0.06 in group 1 and 2.05 +/- 0.09 in group 2. The mean postoperative CFR was 2.09 +/- 0.08 in group 1 and 2.37 +/- 0.06 in group 2. There was a statistically significant difference between the 2 groups as to preoperative creatinine clearance, preoperative estimated GFR, postoperative day 7 creatinine clearance, postoperative month 6 creatinine clearance, postoperative day 7 estimated GFR, postoperative month 6 estimated GFR, preoperative CFR, and postoperative CFR (P <.05). CFR was found to be unaffected by the choice of on-pump or off-pump technique (P =.907). After bypass surgery, there was a significant increase in the mean postoperative CFR, when compared with the mean preoperative CFR (P =.001). Conclusion: In our study, we detected a decrease in CFR in patients with mild renal failure. We believe that in patients undergoing CABG for coronary artery disease, mild renal failure can produce adverse effects due to deterioration of the microvascular bed.en_US
dc.identifier.doi10.1532/HSF98.2013272en_US
dc.identifier.endpageE24en_US
dc.identifier.issn1098-3511en_US
dc.identifier.issn1522-6662en_US
dc.identifier.issue1en_US
dc.identifier.pmid24631986en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpageE18en_US
dc.identifier.urihttps://dx.doi.org/10.1532/HSF98.2013272
dc.identifier.urihttps://hdl.handle.net/20.500.12395/30754
dc.identifier.volume17en_US
dc.identifier.wosWOS:000333172400005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherFORUM MULTIMEDIA PUBLISHING, LLCen_US
dc.relation.ispartofHEART SURGERY FORUMen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleDoes Mild Renal Failure Affect Coronary Flow Reserve after Coronary Artery Bypass Graft Surgery?en_US
dc.typeArticleen_US

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