Usefulness of Peak Mitral Inflow Velocity to Predict Severe Mitral Regurgitation in Patients With Normal or Impaired Left Ventricular Systolic Function

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dc.contributor.authorÖzdemir, Kurtuluş
dc.contributor.authorAltunkeser, Bülent Behlül
dc.contributor.authorSökmen, Gülizar
dc.contributor.authorTokaç, Mehmet
dc.contributor.authorGök, Hasan
dc.date.accessioned2020-03-26T16:37:34Z
dc.date.available2020-03-26T16:37:34Z
dc.date.issued2001
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground The aim of this study was to evaluate the reliability of peak mitral inflow (E-wave) velocity, which was thought to be easier and more practical than qualitative and quantitative methods used to grade mitral regurgitation (MR) in patients both with normal and low left ventricular (LV) ejection fraction (EF). It is known that peak E-wave velocity increases in MR. But correlation of this increase with regurgitant fraction (RF), its usefulness in grading MR, and the effect of EF on peak E-wave velocity have not been studied in detail. Methods We prospectively examined 135 consecutive patients with varying grades of MR with echocardiography. MR was evaluated both qualitatively and quantitatively, and concordance of these 2 methods was determined. Peak E-wave velocity, A-wave velocity, and E-wave deceleration time were measured and the E/A ratio was calculated. LV isovolumetric relaxation and contraction times were measured. Different MR groups classified by RF were compared with each other. Results Concordance of quantitative and qualitative evaluation was low in patients with low EF (kappa 0.37 vs 0.65). Peak E-wave velocity and E/A ratio showed significant differences between MR groups. Peak E-wave velocity correlated with the RF and EF (r = 0.47, r = 0.33, respectively, P < .001). Sensitivity, specificity, and negative predictive value of peak E-wave velocity > 1.2 m/s suggesting severe MR were found to be different in patients with normal and low EF (96% vs 66%, 78% vs 83%, 97% vs 78%, respectively). E-wave deceleration, LV isovolumetric relaxation, and contraction time did not show a correlation with RF. Conclusion Peak E-wave velocity is a screening method that could be used in common for determining severity of MR semiquantitatively, especially in patients with normal EF.en_US
dc.identifier.citationÖzdemir, K., Altunkeser, B. B., Sökmen, G., Tokaç, M., Gök, H., (2001). Usefulness of Peak Mitral Inflow Velocity to Predict Severe Mitral Regurgitation in Patients With Normal or Impaired Left Ventricular Systolic Function. American Heart Journal, 142(6), 1065-1071. DOI: 10.1067/mhj.2001.118465
dc.identifier.doi10.1067/mhj.2001.118465en_US
dc.identifier.endpage1071en_US
dc.identifier.issn0002-8703en_US
dc.identifier.issn1097-5330en_US
dc.identifier.issue6en_US
dc.identifier.pmid11717613en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1065en_US
dc.identifier.urihttps://dx.doi.org/10.1067/mhj.2001.118465
dc.identifier.urihttps://hdl.handle.net/20.500.12395/17648
dc.identifier.volume142en_US
dc.identifier.wosWOS:000172623900022en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÖzdemir, Kurtuluş
dc.institutionauthorAltunkeser, Bülent B.
dc.institutionauthorSökmen, Gülizar
dc.institutionauthorTokaç, Mehmet
dc.institutionauthorGök, Hasan
dc.language.isoenen_US
dc.publisherMOSBY-ELSEVIERen_US
dc.relation.ispartofAmerican Heart Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleUsefulness of Peak Mitral Inflow Velocity to Predict Severe Mitral Regurgitation in Patients With Normal or Impaired Left Ventricular Systolic Functionen_US
dc.typeArticleen_US

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