Effect of the glutaraldehyde derivatives of Calix[n]arene as cross-linker reagents on lipase immobilization
Küçük Resim Yok
Tarih
2009
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
SPRINGER
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Synthesis of the glutaraldehyde derivatives calix[n]arene (n = 4,6,8) (Calix[n]-GA) and using as cross-linkers for immobilization of Candida rugosa lipase (CRL) have been discussed in this paper. The amino functional calix[n]arene derivatives (Calix[n]-NH (2)) were synthesized via reduction of dinitrile, hexanitrile and octanitrile derivatives of calix[n]arenes. These amino functional calix[n]arene derivatives (Calix[n]-NH (2)) were converted to their aldehyde derivativatives with glutaraldehyde. The calix[n]arene derivatives were used in lipase immobilization in order to see the role of calix[n]arene binding site on the lipase activitiy and stability. The activity recovery of calix[n]arene-supported lipases (Calix[n]-CRL) based on the Calix[4]-CRL, Calix[6]-CRL and Calix[8]-CRL reaches to 53.5, 66.1 and 76.4%, respectively.
Açıklama
Anahtar Kelimeler
Calixarene, Cross-linker, Immobilization, Candida rugosa lipase, Glutaraldehyde
Kaynak
JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
64
Sayı
03.04.2020
