Periodontopathogen profile of healthy and oral lichen planus patients with gingivitis or periodontitis

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dc.contributor.authorErtugrul, Abdullah Seckin
dc.contributor.authorArslan, Ugur
dc.contributor.authorDursun, Recep
dc.contributor.authorHakki, Sema Sezgin
dc.date.accessioned2020-03-26T18:42:51Z
dc.date.available2020-03-26T18:42:51Z
dc.date.issued2013
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractOral lichen planus (OLP) is a chronic inflammatory disease that is frequently detected in oral tissues. The aim of our study was to identify the prevalence of the detection of periodontopathogenic microorganisms (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia and Treponema denticola in OLP patients and to compare with this prevalence of periodontopathogenic microorganisms in healthy non-OLP patients. Our study included 27 (18 chronic periodontitis (OLPP) and 9 gingivitis (OLPG)) patients diagnosed with OLP along with 26 (13 chronic periodontitis (HP) and 13 gingivitis (HG)) healthy non-OLP patients. The multiplex polymerase chain reaction (PCR) with subsequent reverse hybridization method (micro-I Dent) was used for identifying periodontopathogenic microorganisms present in subgingival plaque samples. The percentages of detection for A. actinomycetemcomitans, P. gingivalis, P. intermedia, T. forsythia and T. denticola in subgingival plaque samples taken from OLP patients (OLPG and OLPP) were 18.5%, 85.1%, 81.4%, 88.8% and 74%, respectively. Meanwhile, in the non-OLP patients (HG and HP), these values were 7.6%, 50%, 46.1%, 73% and 57.7%, respectively. Thus, comparing the non-OLP groups with the OLP groups, the periodontopathogens' percentages of detection in the OLP groups were higher than those in the non-OLP groups. According to our study results, OLP patients have higher levels of infection with A. actinomycetemcomitans, P. gingivalis, P. intermedia, T. forsythia and T. denticola than non-OLP patients. We argue that the high percentages in patients with OLP may help identify the importance of periodontopathogenic microorganisms in the progress of periodontal diseases of OLP.en_US
dc.description.sponsorshipTurkey Scientific and Technological Research CouncilTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [106S340]; Selcuk University Coordination of Scientific ResearchSelcuk University [06202034]; Open Fund of State Key Laboratory of Oral Diseases, Sichuan Universityen_US
dc.description.sponsorshipThis study has been performed with project support from the Turkey Scientific and Technological Research Council (project no. 106S340) and Selcuk University Coordination of Scientific Research (project no. 06202034). Publication of this manuscript is supported by Open Fund of State Key Laboratory of Oral Diseases, Sichuan University.en_US
dc.identifier.doi10.1038/ijos.2013.30en_US
dc.identifier.endpage97en_US
dc.identifier.issn1674-2818en_US
dc.identifier.issn2049-3169en_US
dc.identifier.issue2en_US
dc.identifier.pmid23743616en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage92en_US
dc.identifier.urihttps://dx.doi.org/10.1038/ijos.2013.30
dc.identifier.urihttps://hdl.handle.net/20.500.12395/29720
dc.identifier.volume5en_US
dc.identifier.wosWOS:000321532600006en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherNATURE PUBLISHING GROUPen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF ORAL SCIENCEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAggregatibacter actinomycetemcomitansen_US
dc.subjectoral lichen plan USen_US
dc.subjectPorphyromonas gingivalisen_US
dc.subjectPrevotella intermediaen_US
dc.subjectTannerella forsythiaen_US
dc.subjectTreponema denticolaen_US
dc.titlePeriodontopathogen profile of healthy and oral lichen planus patients with gingivitis or periodontitisen_US
dc.typeArticleen_US

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