Male Breast Cancer: A Retrospective Study of 15 Years

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dc.contributor.authorEryılmaz, M. A.
dc.contributor.authorİğci, A.
dc.contributor.authorMüslümanoğlu, M.
dc.contributor.authorÖzmen, V.
dc.contributor.authorKoç, M.
dc.date.accessioned2020-03-26T18:30:50Z
dc.date.available2020-03-26T18:30:50Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPurpose: To retrospectively evaluate the 15-year experience with breast cancer in males at a single institution. Methods: The data from 25 male patients who had undergone surgery for breast cancer at a single center were retrospectively analysed. Their medical records were studied for clinical characteristics, therapeutic modalities used and factors associated with disease free (DFS) and overall survival (OS), like local recurrence/distant metastasis. Results: The median patient age was 67 years (range 38-83). The most frequent presenting symptom was a palpable lump. Eighteen (72%) patients underwent modified radical mastectomy (MRM), while sentinel lymph node biopsy (SLNB) was performed in 14(56%) cases. Of 25 patients, 21 (84%) underwent axillary lymph node dissection (ALND) and 15(71.4%) of them had pathological axillary lymph node involvement. Two of 25 (8%) patients with bone and liver metastases underwent toilet mastectomy due to breast ulceration. Estrogen receptor (ER) was positive in 15 (60%) patients, while progesterone receptor (PR) and C-erbB2 (HER-2) were positive in 10 (40%) and 2 (8%) patients, respectively Ten patients (40%) had both ER(+) and PR(+). The median follow-up period was 19 months (range 3-102). Local recurrence developed in one (4%) patient and distant metastasis in 4(16%). Five-year OS and DFS were 53 and 49%, respectively. In univariate and multivariate analysis, pathological tumor size (<2 vs. >2 cm), pathological lymph node involvement and preoperative skin involvement over the breast were not associated with breast recurrence. Only in univariate analysis local recurrence/distant metastasis were associated with poor OS. Conclusion: Large cooperative studies are needed using strict clinical and laboratory criteria to advance the understanding of this disease and to identify the most effective treatment approaches.en_US
dc.identifier.citationEryilmaz, M. A., Igci, A., Muslumanoglu, M., Ozmen, V. Koc, M., (2012). Male Breast Cancer: A Retrospective Study of 15 Years. Journal of Buon, 17(1), 51-56.
dc.identifier.endpage56en_US
dc.identifier.issn1107-0625en_US
dc.identifier.issn2241-6293en_US
dc.identifier.issue1en_US
dc.identifier.pmid22517693en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage51en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28208
dc.identifier.volume17en_US
dc.identifier.wosWOS:000302503700008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKoç, M.
dc.language.isoenen_US
dc.publisherIMPRIMATUR PUBLICATIONSen_US
dc.relation.ispartofJournal of Buonen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectmale breast canceren_US
dc.subjectsentinel lymph node biopsyen_US
dc.subjecttissue-sparing surgeryen_US
dc.titleMale Breast Cancer: A Retrospective Study of 15 Yearsen_US
dc.typeArticleen_US

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