The Relationship between the Antioxidant System and Anaemia in Haemodialysis Patients

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dc.contributor.authorCelik, G.
dc.contributor.authorYontem, M.
dc.contributor.authorBilge, M.
dc.contributor.authorCilo, M.
dc.contributor.authorUnaldi, M.
dc.date.accessioned2020-03-26T18:17:12Z
dc.date.available2020-03-26T18:17:12Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAnaemia and oxidative stress are common features of chronic kidney disease, and both are associated with an increase in morbidity and mortality. There is growing evidence, from experimental and clinical studies, that oxidative stress may be implicated in the pathogenesis of anaemia. This study investigated the relationship between total antioxidant capacity, anaemia and serum albumin levels in 127 non-diabetic patients requiring haemodialysis. Total serum antioxidant capacity levels were determined and were found to be significantly correlated with levels of haemoglobin, haematocrit, serum albumin, serum total protein, malondialdehyde (a product of lipid peroxidation), potassium, phosphorus and alanine transaminase. There was also a significant correlation between serum albumin levels and haemoglobin and haematocrit levels. In conclusion, total antioxidant capacity was found to be inversely correlated with malondialdehyde levels and positively correlated with haemoglobin and haematocrit levels in non-diabetic patients requiring haemodialysis. Patients with high serum albumin concentrations and high total antioxidant capacity may also have high (i.e. normal) levels of haemoglobin.en_US
dc.identifier.doi10.1177/147323001103900541en_US
dc.identifier.endpage1960en_US
dc.identifier.issn0300-0605en_US
dc.identifier.issn1473-2300en_US
dc.identifier.issue5en_US
dc.identifier.pmid22117999en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1954en_US
dc.identifier.urihttps://dx.doi.org/10.1177/147323001103900541
dc.identifier.urihttps://hdl.handle.net/20.500.12395/26994
dc.identifier.volume39en_US
dc.identifier.wosWOS:000297532400041en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSAGE PUBLICATIONS LTDen_US
dc.relation.ispartofJOURNAL OF INTERNATIONAL MEDICAL RESEARCHen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectHAEMODIALYSISen_US
dc.subjectOXIDATIVE STRESSen_US
dc.subjectINFLAMMATIONen_US
dc.subjectTOTAL ANTIOXIDANT CAPACITYen_US
dc.subjectEND-STAGE RENAL DISEASE (ESRD)en_US
dc.subjectANAEMIAen_US
dc.titleThe Relationship between the Antioxidant System and Anaemia in Haemodialysis Patientsen_US
dc.typeArticleen_US

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