Laser-Triggered Degelation Control of Gold Nanoparticle Embedded Peptide Organogels

Basit Öğe Kaydı
dc.contributor.authorErdogan, Hakan
dc.contributor.authorSakalak, Huseyin
dc.contributor.authorYavuz, Mustafa S.
dc.contributor.authorDemirel, Gokhan
dc.date.accessioned2020-03-26T18:42:20Z
dc.date.available2020-03-26T18:42:20Z
dc.date.issued2013
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractFurther understanding of the interactions between nanoparticles (NPs) and biological molecules offers new possibilities in the applications of nanomedicine and nanodiagnostics. The properties of NPs, including size, shape, and surface functionality, play a decisive role in these interactions. Herein, we evaluated the influences of gold NPs (AuNPs) with different sizes (5-60 nm) and shapes (i.e., spherical, rod, and cage) on the self assembly of diphenylalanine (Phe-Phe) dipeptides. We found that the size of AuNPs smaller than 10 nm did not affect the self-assembly process of Phe-Phe, while bigger AuNPs (>10 nm) caused the formation of starlike peptide morphologies connected to one center. In the case of shape differences, nanorod and nanocage morphologies acted differently than spherical ones and caused the formation of densely packed, networklike dipeptide morphologies. In addition to these experiments, by combining photothermal properties of AuNPs with a Phe-Phe-based organogel having a thermo-responsive property, we demonstrated that the degelation process of AuNPs embedded organogels may be controlled by laser illumination. Complete degelation was achieved in about 10 min. We believe that such control may open the door to new opportunities for a number of applications, such as controlled release of drugs and tissue engineering.en_US
dc.description.sponsorshipTUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [111M237]en_US
dc.description.sponsorshipThis work was supported by TUBITAK (Grant 111M237). G.D. also would like to thank Prof. Haluk Koralay from Superconductivity and Thermal Analysis Laboratory at Gazi University for TGA analysis.en_US
dc.identifier.doi10.1021/la401300uen_US
dc.identifier.endpage6982en_US
dc.identifier.issn0743-7463en_US
dc.identifier.issue23en_US
dc.identifier.pmid23706149en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage6975en_US
dc.identifier.urihttps://dx.doi.org/10.1021/la401300u
dc.identifier.urihttps://hdl.handle.net/20.500.12395/29608
dc.identifier.volume29en_US
dc.identifier.wosWOS:000320485400025en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAMER CHEMICAL SOCen_US
dc.relation.ispartofLANGMUIRen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleLaser-Triggered Degelation Control of Gold Nanoparticle Embedded Peptide Organogelsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu