Biological Activity of Extracts of Traditional Wild Medicinal Plants from the Balkan Peninsula
Yükleniyor...
Dosyalar
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
ELSEVIER
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The aim of the present study was to investigate antioxidant, cytotoxic and enzyme-inhibitory activities of wild growing medicinal herbs in the Balkan Peninsula (Morus nigra L., Symphytum officinale L., Sambucus nigra L., Teucrium chamaedrys L. and Teucrium montanum L.). Notably, antioxidant activity of investigated plant species was confirmed through several assays including free radical scavenging (ABTS), reducing power (CUPRAC), phosphomolybdenum and metal chelating test. Cytotoxic activity was evaluated using three different cell lines: Hep2c, RD and L2OB. S. officinale L. and S. nigra L. showed the highest cytotoxic activity. All studied extracts exhibited remarkable inhibitory effects on tested enzymes. S. nigra L. and T. chamaedrys L. exhibited the strongest tyrosinase inhibitory effects (26.62 +/- 0.77 extract and 14.72 +/- 0.41 mgKAEs/g, respectively), while S. officinale L. was the most potent in terms on a-glucosidase inhibition (11.47 +/- 0.05 mmol ACAE/g extract). The obtained results indicate that the extracts of the tested wild grown plants could be used which can be explored as natural medicines for the promotion of health. (c) 2018 SAAB. Published by Elsevier B.V. All rights reserved.
Açıklama
Anahtar Kelimeler
Extracts, Enzyme-inhibitory activity, Antioxidant activity, Cytotoxic activity, Natural agents, Enzim inhibe edici aktivite, Antioksidan aktivite, Sitotoksik aktivite, Doğal ajanlar
Kaynak
South African Journal of Botany
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
120
Sayı
Künye
Vujanovic, M., Zengin, G., Durovic, S., Maskovic, P., Cvetanovic, A., Radojkovic, M. (2019). Biological activity of extracts of traditional wild medicinal plants from the Balkan Peninsula. South African Journal of Botany, 120, 213-218. doi: https://dx.doi.org/10.1016/j.sajb.2018.06.012
