Biological Activity of Extracts of Traditional Wild Medicinal Plants from the Balkan Peninsula

dc.authorid0000-0002-8901-6484
dc.contributor.authorVujanovic, Milena
dc.contributor.authorZengin, Gökhan
dc.contributor.authorDurovic, Saša
dc.contributor.authorMaskovic, Pavle
dc.contributor.authorCvetanovic, Aleksandra
dc.contributor.authorRadojkovic, Marija
dc.date.accessioned2020-03-26T20:12:45Z
dc.date.available2020-03-26T20:12:45Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Fen Fakültesi, Biyoloji Bölümüen_US
dc.description.abstractThe aim of the present study was to investigate antioxidant, cytotoxic and enzyme-inhibitory activities of wild growing medicinal herbs in the Balkan Peninsula (Morus nigra L., Symphytum officinale L., Sambucus nigra L., Teucrium chamaedrys L. and Teucrium montanum L.). Notably, antioxidant activity of investigated plant species was confirmed through several assays including free radical scavenging (ABTS), reducing power (CUPRAC), phosphomolybdenum and metal chelating test. Cytotoxic activity was evaluated using three different cell lines: Hep2c, RD and L2OB. S. officinale L. and S. nigra L. showed the highest cytotoxic activity. All studied extracts exhibited remarkable inhibitory effects on tested enzymes. S. nigra L. and T. chamaedrys L. exhibited the strongest tyrosinase inhibitory effects (26.62 +/- 0.77 extract and 14.72 +/- 0.41 mgKAEs/g, respectively), while S. officinale L. was the most potent in terms on a-glucosidase inhibition (11.47 +/- 0.05 mmol ACAE/g extract). The obtained results indicate that the extracts of the tested wild grown plants could be used which can be explored as natural medicines for the promotion of health. (c) 2018 SAAB. Published by Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipMinistry of Education, Science and Technological Development of the Republic of Serbia [TR31013, TR31093]en_US
dc.description.sponsorshipThe present work was carried out within the projects of the Ministry of Education, Science and Technological Development of the Republic of Serbia, (Project Nos. TR31013 and TR31093).en_US
dc.identifier.citationVujanovic, M., Zengin, G., Durovic, S., Maskovic, P., Cvetanovic, A., Radojkovic, M. (2019). Biological activity of extracts of traditional wild medicinal plants from the Balkan Peninsula. South African Journal of Botany, 120, 213-218. doi: https://dx.doi.org/10.1016/j.sajb.2018.06.012
dc.identifier.doi10.1016/j.sajb.2018.06.012en_US
dc.identifier.endpage218en_US
dc.identifier.issn0254-6299en_US
dc.identifier.issn1727-9321en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage213en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.sajb.2018.06.012
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37538
dc.identifier.volume120en_US
dc.identifier.wosWOS:000456314600028en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorZengin, Gökhan
dc.language.isoenen_US
dc.publisherELSEVIERen_US
dc.relation.ispartofSouth African Journal of Botanyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectExtractsen_US
dc.subjectEnzyme-inhibitory activityen_US
dc.subjectAntioxidant activityen_US
dc.subjectCytotoxic activityen_US
dc.subjectNatural agentsen_US
dc.subjectEnzim inhibe edici aktivite
dc.subjectAntioksidan aktivite
dc.subjectSitotoksik aktivite
dc.subjectDoğal ajanlar
dc.titleBiological Activity of Extracts of Traditional Wild Medicinal Plants from the Balkan Peninsulaen_US
dc.typeArticleen_US

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