Multicomponent pattern and biological activities of seven Asphodeline taxa: potential sources of natural-functional ingredients for bioactive formulations

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dc.contributor.authorLocatelli, Marcello
dc.contributor.authorZengin, Gökhan
dc.contributor.authorUysal, Ahmet
dc.contributor.authorCarradori, Simone
dc.contributor.authorDe Luca, Elisa
dc.contributor.authorBellagamba, Giuseppe
dc.contributor.authorAktümsek, Abdurrahman
dc.date.accessioned2020-03-26T19:42:07Z
dc.date.available2020-03-26T19:42:07Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe current study was carried out to evaluate multicomponent pattern, biological and enzymatic activities of seven Asphodeline taxa root extracts as useful ingredients, due to the fact that these plants are commonly used as traditional food supplements in Turkish regions. The extracts were characterized for free anthraquinones and phenolics to obtain a specific chemical fingerprint useful for quality control. These analyzes were coupled to biological and enzymatic activities in order to obtain comprehensive information of the natural product. Free anthraquinones and phenolics were determined using validated HPLC-PDA methods. Antioxidant properties were determined by different procedures including free radical scavenging, reducing power, phosphomolybdenum and metal chelating assays. Ames assay was performed to evaluate mutagenic/antimutagenic properties. Enzyme inhibitory activities were tested against cholinesterase, tyrosinase, alpha-amylase and alpha-glucosidase. From the herein reported results, Asphodeline could be valuable for the production of bioactive products or food supplements for cosmetic and pharmaceutical industries.en_US
dc.description.sponsorshipResearch Foundation of Selcuk University (BAP)Selcuk University; University "G. d'Annunzio" of Chieti-Pescaraen_US
dc.description.sponsorshipThe authors gratefully acknowledge for the financial support given for this research from the Research Foundation of Selcuk University (BAP) and the University "G. d'Annunzio" of Chieti-Pescara.en_US
dc.identifier.doi10.1080/14756366.2016.1235041en_US
dc.identifier.endpage67en_US
dc.identifier.issn1475-6366en_US
dc.identifier.issn1475-6374en_US
dc.identifier.issue1en_US
dc.identifier.pmid27774819en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage60en_US
dc.identifier.urihttps://dx.doi.org/10.1080/14756366.2016.1235041
dc.identifier.urihttps://hdl.handle.net/20.500.12395/35309
dc.identifier.volume32en_US
dc.identifier.wosWOS:000392591100051en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS LTDen_US
dc.relation.ispartofJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAsphodelineen_US
dc.subjectanthraquinonesen_US
dc.subjectbiological activity and bioactive compoundsen_US
dc.subjectmulticomponent patternen_US
dc.subjectphenolicsen_US
dc.titleMulticomponent pattern and biological activities of seven Asphodeline taxa: potential sources of natural-functional ingredients for bioactive formulationsen_US
dc.typeArticleen_US

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