Histological evaluation of the effects of bioglass, hydroxyapatite, or demineralized freeze-dried bone, grafted alone or as composites, on the healing of tibial defects in rabbits

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dc.contributor.authorKucukkolbasi, Hasan
dc.contributor.authorMutlu, Necip
dc.contributor.authorIsik, Kubilay
dc.contributor.authorCelik, Ilhami
dc.contributor.authorOznurlu, Yasemin
dc.date.accessioned2020-03-26T17:38:50Z
dc.date.available2020-03-26T17:38:50Z
dc.date.issued2009
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjectives: To compare the effectiveness of bioactive glass (BG), natural hydroxyapatite (HA), and demineralized freeze-dried bone (DFDB) in bone defects. Methods: All animal experiments were conducted in Faculty (if Veterinary Medicine, Selcuk University, Konya, Turkey, under the Selcuk University Guidelines for Animal Experimentation, in 2005. Eighteen New Zealand rabbits were used for the experiment. Four cavities were prepared on right and left tibias. The cavities on the right tibia were filled with either BG, HA or DFDB. One cavity was left empty as a control. The cavities on the other tibia] bone were grafted with HA+BG, DFA+DFDB, BG+DFDB and HA+BG+DFDB composites. Histological examinations were performed at first, third, and sixth postoperative months. Results: According to histomorphometric findings, the mixture containing HA+BG+DFDB obtained the best histological results (P<0.05). Conclusion: The composite graft of HA, BG and DFDB is more effective than when used as individual agents.en_US
dc.identifier.endpage333en_US
dc.identifier.issn0379-5284en_US
dc.identifier.issue3en_US
dc.identifier.pmid19271058en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage329en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/23584
dc.identifier.volume30en_US
dc.identifier.wosWOS:000265258400002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSAUDI MED Jen_US
dc.relation.ispartofSAUDI MEDICAL JOURNALen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleHistological evaluation of the effects of bioglass, hydroxyapatite, or demineralized freeze-dried bone, grafted alone or as composites, on the healing of tibial defects in rabbitsen_US
dc.typeArticleen_US

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